McGirr Alexander, Paris Joel, Lesage Alain, Renaud Johanne, Turecki Gustavo
University of Toronto, Toronto, Ontario; McGill Group for Suicide Studies, Douglas Hospital Research Centre, McGill University, Montreal, Quebec.
Can J Psychiatry. 2009 Feb;54(2):87-92. doi: 10.1177/070674370905400206.
To clarify whether certain Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), borderline personality disorder (BPD) symptoms are more prevalent among people who die by suicide, and thereby better predict suicide risk.
A psychological autopsy method with best informants was used to investigate DSM-IV BPD symptoms and suicide risk among people who died by suicide and met criteria for BPD (n = 62), and BPD control subjects (n = 35).
BPD symptoms in people who died by suicide were less likely to include affective instability and paranoid ideation-dissociative symptoms. The negative association between paranoid ideation-dissociative symptoms and suicide was independent of all other BPD symptoms, Cluster B comorbidity, and alcohol dependence.
We found that discrete DSM-IV BPD symptoms differentiate people with BPD who die by suicide and those who do not. People with BPD who go on to die by suicide appear to constitute a specific subgroup of those who meet criteria for BPD, characterized by different general clinical presentation, but also by different characteristics within BPD.
明确《精神疾病诊断与统计手册》第四版（DSM-IV）中某些边缘型人格障碍（BPD）症状在自杀死亡者中是否更为普遍，从而更好地预测自杀风险。
采用最佳信息提供者的心理解剖方法，对自杀死亡且符合BPD标准的人群（n = 62）以及BPD对照受试者（n = 35）中的DSM-IV BPD症状和自杀风险进行调查。
自杀死亡者的BPD症状较少包括情感不稳定和偏执观念-分离症状。偏执观念-分离症状与自杀之间的负相关独立于所有其他BPD症状、B类共病和酒精依赖。
我们发现，DSM-IV中离散的BPD症状可区分自杀死亡的BPD患者和未自杀死亡的患者。继续自杀死亡的BPD患者似乎构成了符合BPD标准人群中的一个特定亚组，其特征不仅在于不同的一般临床表现，还在于BPD内部的不同特征。
