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雪莲果糖浆:对人类肥胖和胰岛素抵抗的有益作用。

Yacon syrup: beneficial effects on obesity and insulin resistance in humans.

作者信息

Genta Susana, Cabrera Wilfredo, Habib Natalia, Pons Juan, Carillo Iván Manrique, Grau Alfredo, Sánchez Sara

机构信息

Instituto Superior de Investigaciones Biológicas, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Tucumán, Chacabuco 461, 4000-San Miguel de Tucumán, Tucumán, Argentina.

出版信息

Clin Nutr. 2009 Apr;28(2):182-7. doi: 10.1016/j.clnu.2009.01.013. Epub 2009 Feb 28.

DOI:10.1016/j.clnu.2009.01.013
PMID:19254816
Abstract

BACKGROUND & AIMS: Syrup obtained from yacon roots could be well positioned as a nutraceutical product due to its high fructooligosaccharides content. We examined the beneficial effects and tolerance of yacon syrup on human health.

METHODS

Obese and slightly dyslipidemic pre-menopausal women were studied over a 120-day period in a double-blind placebo-controlled experiment. We used two doses of yacon syrup, 0.29 g and 0.14 g fructooligosaccharides/kg/day. At the start and end of the study, anthropometric measurements, blood glucose, calcium, lipid and insulin concentrations and Homeostasis Model Assessment index were determined.

RESULTS

The recommended daily consumption of yacon syrup with no undesirable gastrointestinal effects is 0.14 g fructooligosaccharides/kg. Daily intake of yacon syrup produced a significant decrease in body weight, waist circumference and body mass index. Additionally, decrease in fasting serum insulin and Homeostasis Model Assessment index was observed. The consumption of yacon syrup increased defecation frequency and satiety sensation. Fasting glucose and serum lipids were not affected by syrup treatment and the only positive effect was found in serum LDL-cholesterol levels.

CONCLUSIONS

Yacon syrup is a good source of fructooligosaccharides and its long-term consumption produced beneficial health effects on obese pre-menopausal women with insulin resistance.

摘要

背景与目的

由于雪莲果糖浆中低聚果糖含量高,可作为营养保健品。我们研究了雪莲果糖浆对人体健康的有益作用和耐受性。

方法

在一项为期120天的双盲安慰剂对照实验中,对肥胖和轻度血脂异常的绝经前女性进行了研究。我们使用了两种剂量的雪莲果糖浆,分别为0.29克和0.14克低聚果糖/千克/天。在研究开始和结束时,测定了人体测量指标、血糖、钙、脂质和胰岛素浓度以及稳态模型评估指数。

结果

雪莲果糖浆的推荐日摄入量为0.14克低聚果糖/千克,且无不良胃肠道影响。每日摄入雪莲果糖浆可显著降低体重、腰围和体重指数。此外,空腹血清胰岛素和稳态模型评估指数也有所下降。食用雪莲果糖浆可增加排便频率和饱腹感。空腹血糖和血脂不受糖浆治疗的影响,唯一的积极作用是血清低密度脂蛋白胆固醇水平有所改善。

结论

雪莲果糖浆是低聚果糖的良好来源,长期食用对患有胰岛素抵抗的肥胖绝经前女性具有有益的健康影响。

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