• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

美国城市青年成年人社区样本中的创伤后应激障碍与自杀未遂

Posttraumatic stress disorder and suicide attempts in a community sample of urban american young adults.

作者信息

Wilcox Holly C, Storr Carla L, Breslau Naomi

机构信息

Department of Psychiatry and Behavioral Science, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA.

出版信息

Arch Gen Psychiatry. 2009 Mar;66(3):305-11. doi: 10.1001/archgenpsychiatry.2008.557.

DOI:10.1001/archgenpsychiatry.2008.557
PMID:19255380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6003890/
Abstract

CONTEXT

Previous research has shown that exposure to traumatic events, especially sexual trauma during childhood, is associated with an increased risk of attempted suicide. However, no information is available as to whether the increased risk of attempted suicide is related primarily to posttraumatic stress disorder (PTSD) following traumatic experiences or applies also to persons who experienced trauma but did not develop PTSD.

OBJECTIVE

We examine the association between exposure to traumatic events with and without resulting PTSD and the risk of a subsequent suicide attempt in a community sample of urban young adults.

DESIGN

A cohort study followed young adults who had participated in a randomized trial of all first-grade students entering 19 public schools.

SETTING

Baltimore, Maryland, an urban setting.

PARTICIPANTS

A total of 1698 young adults (mean age, 21; 47% male; 71% African American) who represented 75% of the original cohort of 2311 persons.

MAIN OUTCOME MEASURE

Relative risk of a subsequent suicide attempt associated with PTSD and with exposure to assaultive and non-assaultive traumas (no PTSD), as estimated using discrete time survival analysis.

RESULTS

Posttraumatic stress disorder was associated with increased risk of a subsequent suicide attempt. The PTSD-suicide attempt association was robust, even after adjustment for a prior major depressive episode, alcohol abuse or dependence, and drug abuse or dependence (adjusted relative risk, 2.7; 95% confidence interval, 1.3-5.5; P < .01). In contrast, exposure to traumatic events without PTSD was not associated with an increased risk of attempted suicide.

CONCLUSIONS

Posttraumatic stress disorder is an independent predictor of attempted suicide. Exposure to traumatic events without PTSD is not associated with a later suicide attempt.

摘要

背景

先前的研究表明,遭受创伤性事件,尤其是童年时期的性创伤,与自杀未遂风险增加有关。然而,关于自杀未遂风险增加主要是与创伤经历后的创伤后应激障碍(PTSD)相关,还是也适用于经历过创伤但未患PTSD的人,尚无相关信息。

目的

我们在一个城市青年成年人社区样本中,研究有和没有导致PTSD的创伤性事件暴露与后续自杀未遂风险之间的关联。

设计

一项队列研究,追踪参与了对19所公立学校所有一年级学生进行的随机试验的青年成年人。

地点

马里兰州巴尔的摩市,一个城市环境。

参与者

共有1698名青年成年人(平均年龄21岁;47%为男性;71%为非裔美国人),占原始队列2311人的75%。

主要结局指标

使用离散时间生存分析估计与PTSD以及与遭受攻击性和非攻击性创伤(无PTSD)相关的后续自杀未遂的相对风险。

结果

创伤后应激障碍与后续自杀未遂风险增加相关。即使在调整了先前的重度抑郁发作、酒精滥用或依赖以及药物滥用或依赖后,PTSD与自杀未遂之间的关联仍然很强(调整后的相对风险为2.7;95%置信区间为1.3 - 5.5;P <.01)。相比之下,未患PTSD的创伤性事件暴露与自杀未遂风险增加无关。

结论

创伤后应激障碍是自杀未遂的独立预测因素。未患PTSD的创伤性事件暴露与后来的自杀未遂无关。

相似文献

1
Posttraumatic stress disorder and suicide attempts in a community sample of urban american young adults.美国城市青年成年人社区样本中的创伤后应激障碍与自杀未遂
Arch Gen Psychiatry. 2009 Mar;66(3):305-11. doi: 10.1001/archgenpsychiatry.2008.557.
2
Posttraumatic stress disorder increases risk for suicide attempt in adults with recurrent major depression.创伤后应激障碍会增加复发性重度抑郁症成年患者自杀企图的风险。
Depress Anxiety. 2013 Oct;30(10):940-6. doi: 10.1002/da.22160. Epub 2013 Jul 24.
3
Posttraumatic stress disorder comorbid with major depression: factors mediating the association with suicidal behavior.创伤后应激障碍合并重度抑郁症:介导与自杀行为关联的因素。
Am J Psychiatry. 2005 Mar;162(3):560-6. doi: 10.1176/appi.ajp.162.3.560.
4
Types and Number of Traumas Associated With Suicidal Ideation and Suicide Attempts in PTSD: Findings From a U.S. Nationally Representative Sample.创伤后应激障碍中与自杀意念和自杀未遂相关的创伤类型及数量:来自美国全国代表性样本的研究结果
J Trauma Stress. 2015 Jun;28(3):183-90. doi: 10.1002/jts.22010. Epub 2015 May 19.
5
[Not Available].[无可用内容]
Salud Ment (Mex). 2009 Jan 1;32(2):145-153.
6
Incidence of drug problems in young adults exposed to trauma and posttraumatic stress disorder: do early life experiences and predispositions matter?遭受创伤和创伤后应激障碍的年轻人中药物问题的发生率:早年经历和易感性是否有影响?
Arch Gen Psychiatry. 2007 Dec;64(12):1435-42. doi: 10.1001/archpsyc.64.12.1435.
7
[Posttraumatic stress disorder (PTSD) as a consequence of the interaction between an individual genetic susceptibility, a traumatogenic event and a social context].[创伤后应激障碍(PTSD)作为个体遗传易感性、创伤性事件和社会环境之间相互作用的结果]
Encephale. 2012 Oct;38(5):373-80. doi: 10.1016/j.encep.2011.12.003. Epub 2012 Jan 24.
8
A second look at prior trauma and the posttraumatic stress disorder effects of subsequent trauma: a prospective epidemiological study.再审视既往创伤及后续创伤的创伤后应激障碍效应:一项前瞻性流行病学研究。
Arch Gen Psychiatry. 2008 Apr;65(4):431-7. doi: 10.1001/archpsyc.65.4.431.
9
Which Posttraumatic Stress Disorder Symptoms, Trauma Types, and Substances Correlate With Suicide Attempts in Trauma Survivors?哪些创伤后应激障碍症状、创伤类型和物质与创伤幸存者的自杀企图相关?
Prim Care Companion CNS Disord. 2017 Oct 26;19(5):17m02177. doi: 10.4088/PCC.17m02177.
10
The epidemiology of trauma and post-traumatic stress disorder in a representative cohort of young people in England and Wales.英格兰和威尔士年轻人代表性队列中的创伤及创伤后应激障碍流行病学
Lancet Psychiatry. 2019 Mar;6(3):247-256. doi: 10.1016/S2215-0366(19)30031-8.

引用本文的文献

1
Brexpiprazole and Sertraline Combination Treatment in Posttraumatic Stress Disorder: A Phase 3 Randomized Clinical Trial.布雷哌唑与舍曲林联合治疗创伤后应激障碍:一项3期随机临床试验。
JAMA Psychiatry. 2025 Mar 1;82(3):218-227. doi: 10.1001/jamapsychiatry.2024.3996.
2
The Psychedelic Future of Post-Traumatic Stress Disorder Treatment.创伤后应激障碍治疗的迷幻未来。
Curr Neuropharmacol. 2024;22(4):636-735. doi: 10.2174/1570159X22666231027111147.
3
Circulating cell-free mitochondrial DNA levels and glucocorticoid sensitivity in a cohort of male veterans with and without combat-related PTSD.循环细胞游离线粒体 DNA 水平与有和无战斗相关 PTSD 的男性退伍军人的糖皮质激素敏感性。
Transl Psychiatry. 2024 Jan 10;14(1):22. doi: 10.1038/s41398-023-02721-x.
4
Multi-task learning to detect suicide ideation and mental disorders among social media users.多任务学习用于检测社交媒体用户中的自杀意念和精神障碍。
Front Res Metr Anal. 2023 Apr 17;8:1152535. doi: 10.3389/frma.2023.1152535. eCollection 2023.
5
Association of Recent Violence Encounters With Suicidal Ideation Among Adolescents With Depression.近期暴力遭遇与抑郁青少年自杀意念的关联。
JAMA Netw Open. 2023 Mar 1;6(3):e231190. doi: 10.1001/jamanetworkopen.2023.1190.
6
Associations between traumatic event experiences, psychiatric disorders, and suicidal behavior in the general population of Afghanistan: findings from Afghan National Mental Health Survey.阿富汗普通人群中创伤事件经历、精神疾病与自杀行为之间的关联:阿富汗国家心理健康调查结果
Inj Epidemiol. 2022 Oct 6;9(1):31. doi: 10.1186/s40621-022-00403-8.
7
Pathways to Suicidal Behavior in Children and Adolescents: Examination of Child Maltreatment and Post-Traumatic Symptoms.儿童和青少年自杀行为的途径:儿童虐待与创伤后症状的考察
J Child Adolesc Trauma. 2022 Feb 9;15(3):715-725. doi: 10.1007/s40653-022-00439-4. eCollection 2022 Sep.
8
Psychoactive Drugs in the Management of Post Traumatic Stress Disorder: A Promising New Horizon.精神活性药物在创伤后应激障碍治疗中的应用:一个充满希望的新领域。
Cureus. 2022 May 23;14(5):e25235. doi: 10.7759/cureus.25235. eCollection 2022 May.
9
Transcranial Magnetic Stimulation for Post-traumatic Stress Disorder.经颅磁刺激治疗创伤后应激障碍
Front Psychiatry. 2022 May 31;13:701348. doi: 10.3389/fpsyt.2022.701348. eCollection 2022.
10
Suicide attempt, impulsivity, and exposure to trauma in college students.大学生自杀未遂、冲动和创伤暴露。
Braz J Psychiatry. 2022 May-Jun;44(3):279-288. doi: 10.1590/1516-4446-2021-2175.

本文引用的文献

1
Depressed mood in childhood and subsequent alcohol use through adolescence and young adulthood.童年时期的抑郁情绪以及随后在青少年期和青年期的饮酒情况。
Arch Gen Psychiatry. 2008 Jun;65(6):702-12. doi: 10.1001/archpsyc.65.6.702.
2
Effects of a universal classroom behavior management program in first and second grades on young adult behavioral, psychiatric, and social outcomes.一项针对一、二年级的通用课堂行为管理计划对青少年行为、精神和社会结局的影响。
Drug Alcohol Depend. 2008 Jun 1;95 Suppl 1(Suppl 1):S5-S28. doi: 10.1016/j.drugalcdep.2008.01.004. Epub 2008 Mar 17.
3
The impact of two universal randomized first- and second-grade classroom interventions on young adult suicide ideation and attempts.两项针对一年级和二年级课堂的普遍随机干预措施对青少年自杀意念和自杀未遂行为的影响。
Drug Alcohol Depend. 2008 Jun 1;95 Suppl 1(Suppl 1):S60-73. doi: 10.1016/j.drugalcdep.2008.01.005. Epub 2008 Mar 7.
4
Common genetic liability to major depression and posttraumatic stress disorder in men.男性中重度抑郁症和创伤后应激障碍的共同遗传易感性。
J Affect Disord. 2008 Jan;105(1-3):109-15. doi: 10.1016/j.jad.2007.04.021. Epub 2007 May 30.
5
Traumatic events and suicidal behavior: results from a national mental health survey.创伤性事件与自杀行为:一项全国心理健康调查的结果
J Nerv Ment Dis. 2007 Apr;195(4):342-9. doi: 10.1097/01.nmd.0b013e318060a869.
6
Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample.在一个大型社区样本中,与创伤后应激障碍相关的身心共病、残疾及自杀行为。
Psychosom Med. 2007 Apr;69(3):242-8. doi: 10.1097/PSY.0b013e31803146d8. Epub 2007 Mar 30.
7
Interaction between childhood trauma and serotonin transporter gene variation in suicide.童年创伤与血清素转运体基因变异在自杀中的相互作用。
Neuropsychopharmacology. 2007 Sep;32(9):2046-52. doi: 10.1038/sj.npp.1301331. Epub 2007 Mar 14.
8
Childhood antecedents of exposure to traumatic events and posttraumatic stress disorder.童年期创伤性事件暴露及创伤后应激障碍的前驱因素
Am J Psychiatry. 2007 Jan;164(1):119-25. doi: 10.1176/ajp.2007.164.1.119.
9
Intelligence and other predisposing factors in exposure to trauma and posttraumatic stress disorder: a follow-up study at age 17 years.创伤暴露及创伤后应激障碍中的智力与其他诱发因素:一项17岁时的随访研究
Arch Gen Psychiatry. 2006 Nov;63(11):1238-45. doi: 10.1001/archpsyc.63.11.1238.
10
Risk factors for suicidality in Europe: results from the ESEMED study.欧洲自杀倾向的风险因素:ESEMED研究结果
J Affect Disord. 2007 Aug;101(1-3):27-34. doi: 10.1016/j.jad.2006.09.018. Epub 2006 Oct 30.