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美国城市青年成年人社区样本中的创伤后应激障碍与自杀未遂

Posttraumatic stress disorder and suicide attempts in a community sample of urban american young adults.

作者信息

Wilcox Holly C, Storr Carla L, Breslau Naomi

机构信息

Department of Psychiatry and Behavioral Science, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA.

出版信息

Arch Gen Psychiatry. 2009 Mar;66(3):305-11. doi: 10.1001/archgenpsychiatry.2008.557.

Abstract

CONTEXT

Previous research has shown that exposure to traumatic events, especially sexual trauma during childhood, is associated with an increased risk of attempted suicide. However, no information is available as to whether the increased risk of attempted suicide is related primarily to posttraumatic stress disorder (PTSD) following traumatic experiences or applies also to persons who experienced trauma but did not develop PTSD.

OBJECTIVE

We examine the association between exposure to traumatic events with and without resulting PTSD and the risk of a subsequent suicide attempt in a community sample of urban young adults.

DESIGN

A cohort study followed young adults who had participated in a randomized trial of all first-grade students entering 19 public schools.

SETTING

Baltimore, Maryland, an urban setting.

PARTICIPANTS

A total of 1698 young adults (mean age, 21; 47% male; 71% African American) who represented 75% of the original cohort of 2311 persons.

MAIN OUTCOME MEASURE

Relative risk of a subsequent suicide attempt associated with PTSD and with exposure to assaultive and non-assaultive traumas (no PTSD), as estimated using discrete time survival analysis.

RESULTS

Posttraumatic stress disorder was associated with increased risk of a subsequent suicide attempt. The PTSD-suicide attempt association was robust, even after adjustment for a prior major depressive episode, alcohol abuse or dependence, and drug abuse or dependence (adjusted relative risk, 2.7; 95% confidence interval, 1.3-5.5; P < .01). In contrast, exposure to traumatic events without PTSD was not associated with an increased risk of attempted suicide.

CONCLUSIONS

Posttraumatic stress disorder is an independent predictor of attempted suicide. Exposure to traumatic events without PTSD is not associated with a later suicide attempt.

摘要

背景

先前的研究表明,遭受创伤性事件,尤其是童年时期的性创伤,与自杀未遂风险增加有关。然而,关于自杀未遂风险增加主要是与创伤经历后的创伤后应激障碍(PTSD)相关,还是也适用于经历过创伤但未患PTSD的人,尚无相关信息。

目的

我们在一个城市青年成年人社区样本中,研究有和没有导致PTSD的创伤性事件暴露与后续自杀未遂风险之间的关联。

设计

一项队列研究,追踪参与了对19所公立学校所有一年级学生进行的随机试验的青年成年人。

地点

马里兰州巴尔的摩市,一个城市环境。

参与者

共有1698名青年成年人(平均年龄21岁;47%为男性;71%为非裔美国人),占原始队列2311人的75%。

主要结局指标

使用离散时间生存分析估计与PTSD以及与遭受攻击性和非攻击性创伤(无PTSD)相关的后续自杀未遂的相对风险。

结果

创伤后应激障碍与后续自杀未遂风险增加相关。即使在调整了先前的重度抑郁发作、酒精滥用或依赖以及药物滥用或依赖后,PTSD与自杀未遂之间的关联仍然很强(调整后的相对风险为2.7;95%置信区间为1.3 - 5.5;P <.01)。相比之下,未患PTSD的创伤性事件暴露与自杀未遂风险增加无关。

结论

创伤后应激障碍是自杀未遂的独立预测因素。未患PTSD的创伤性事件暴露与后来的自杀未遂无关。

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