横向场对DNA尺寸颗粒动力学的影响。
Transverse field effects on DNA-sized particle dynamics.
作者信息
Tsutsui Makusu, Taniguchi Masateru, Kawai Tomoji
机构信息
The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, Japan.
出版信息
Nano Lett. 2009 Apr;9(4):1659-62. doi: 10.1021/nl900177q.
We report the development of microfluidics-integrated mechanically controllable break junction device and its applications to electrical characterizations of DNA-sized particle dynamics in a microfluidic channel. It is found that the electrostatic electrode-particle interaction slows down the particle flow through the electrode nanogaps. The present results suggest the useful capability of transverse electric field for controlling DNA translocations through a nanopore.
我们报道了集成微流控的机械可控断裂结装置的开发及其在微流控通道中对DNA尺寸颗粒动力学进行电学表征的应用。研究发现，静电电极-颗粒相互作用减缓了颗粒通过电极纳米间隙的流动。目前的结果表明，横向电场在控制DNA通过纳米孔转运方面具有实用能力。
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