基于梯度折射率透镜棒的探头，用于人体喉部的门诊光学相干断层扫描。
Gradient-index lens rod based probe for office-based optical coherence tomography of the human larynx.
作者信息
Guo Shuguang, Yu Lingfeng, Sepehr Ali, Perez Jorge, Su Jianping, Ridgway James M, Vokes David, Wong Brian J F, Chen Zhongping
机构信息
University of California, Irvine, Department of Biomedical Engineering, Irvine, California 92697, USA.
出版信息
J Biomed Opt. 2009 Jan-Feb;14(1):014017. doi: 10.1117/1.3076198.
Abstract
Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient-index lens-based probe capable of capturing images of the human larynx by use of spectral domain OCT during a typical office-based laryngoscopy examination is presented. An optical-ballast-based 4f optical relay system is proposed to realize variable working distance with a constant optical delay. In-vivo OCT imaging of the human larynx is demonstrated. Office-based OCT is a promising imaging modality for early laryngeal cancer diagnosis.
摘要
光学相干断层扫描（OCT）是一种不断发展的非侵入性成像方式，已被用于在手术内窥镜检查期间对人体喉部进行成像。本文介绍了一种基于长梯度折射率透镜的探头设计，该探头能够在典型的门诊喉镜检查中利用光谱域OCT捕获人体喉部的图像。提出了一种基于光学镇流器的4f光学中继系统，以实现具有恒定光学延迟的可变工作距离。展示了人体喉部的体内OCT成像。门诊OCT是一种用于早期喉癌诊断的有前景的成像方式。
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