用于高分辨率光学相干断层扫描球囊成像导管的柔性微型复合透镜设计
Flexible miniature compound lens design for high-resolution optical coherence tomography balloon imaging catheter.
作者信息
Fu Henry L, Leng Yuxin, Cobb Michael J, Hsu Kevin, Hwang Joo Ha, Li Xingde
机构信息
University of Washington, Department of Bioengineering, Seattle, Washington 98195, USA.
出版信息
J Biomed Opt. 2008 Nov-Dec;13(6):060502. doi: 10.1117/1.3037340.
Abstract
We report on a new optics design for an optical coherence tomography (OCT) balloon imaging catheter. The design involves a miniature compound gradient-index (GRIN) rod lens, which consists of a fiber optic mode-field reducer and relay rod lenses to achieve predictable high lateral resolution at a desired large working distance. The compound lens design significantly simplifies the engineering process for an OCT catheter and enables 3-D full circumferential cross sectional imaging of large luminal organs such as human esophagus. An as-designed OCT catheter is developed and demonstrated for real-time in vivo swine esophagus imaging in a 3-D spiral fashion.
摘要
我们报告了一种用于光学相干断层扫描（OCT）球囊成像导管的新型光学设计。该设计涉及一个微型复合梯度折射率（GRIN）棒透镜，它由一个光纤模场缩小器和中继棒透镜组成，以在所需的大工作距离处实现可预测的高横向分辨率。复合透镜设计显著简化了OCT导管的工程过程，并能够对诸如人体食管等大腔器官进行三维全周横截面成像。已开发出一种按设计制造的OCT导管，并展示了其以三维螺旋方式对猪食管进行实时体内成像的能力。
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