Popova Milena, Trusheva Boryana, Gyosheva Melania, Tsvetkova Iva, Bankova Vassya
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Fitoterapia. 2009 Jul;80(5):263-6. doi: 10.1016/j.fitote.2009.02.008. Epub 2009 Mar 3.
From a biologically active extract from the fungus Fomitopsis rosea, two new lanostane triterpenes were isolated, 3alpha-(3'-butylcarboxyacetoxy)oxepanoquercinic acid C 1 and 3alpha-hydroxy-24-methylene-23-oxolanost-8-en-26-carboxylic acid 2, along with three known triterpenes, 3-5, and the epidioxy sterol derivative 6. The structures of the compounds were elucidated based on their spectral properties. All triterpenes demonstrated antibacterial activity against S. aureus but possessed no antiradical activity against DPPH radicals.
从真菌红缘拟层孔菌的生物活性提取物中,分离出两种新的羊毛甾烷三萜,即3α-(3'-丁基羧基乙酰氧基)氧杂环庚烷酸C1和3α-羟基-24-亚甲基-23-氧代羊毛甾-8-烯-26-羧酸2,以及三种已知的三萜3 - 5和表环氧甾醇衍生物6。根据其光谱性质阐明了这些化合物的结构。所有三萜均对金黄色葡萄球菌表现出抗菌活性,但对DPPH自由基没有抗自由基活性。