Bacon Simon L, Pelletier Roxanne, Lavoie Kim L
Department of Exercise Science, Concordia University, 7141 Sherbrooke St West, SP165.35, Montreal, Québec, H4B 1R6, Canada.
Thromb Haemost. 2009 Mar;101(3):452-9.
There is now a large and impressive literature showing that people who engage in chronic aerobic exercise or who have better cardiovascular fitness levels, tend to live longer and have lower levels of cardiovascular disease (CVD). However, there is a paradox, as acute aerobic exercise has been associated with an increased risk of CVD events. There are now a number of review articles suggesting that the differential benefits of chronic, relative to acute, exercise might be due to thrombotic changes, though the majority of this data is derived from healthy individuals. However, acute exercise is of greater concern and chronic exercise of greater benefit to patient populations. In addition, these higher risk groups tend to present with more complex profiles, e.g. they may be taking medications that influence thrombotic pathways. As such, the current review has focused on newer information relating to exercise, physical activity and thrombosis in patient populations, and highlights some of the growing area's in the field. For example, the impact of warm-up exercise, the interaction of medications, and issues surrounding the optimal volume and intensity of exercise.
现在有大量令人印象深刻的文献表明，进行长期有氧运动或心血管健康水平较高的人往往寿命更长，心血管疾病（CVD）水平更低。然而，存在一个悖论，因为急性有氧运动与CVD事件风险增加有关。现在有一些综述文章表明，相对于急性运动，长期运动的不同益处可能归因于血栓形成变化，尽管这些数据大多来自健康个体。然而，急性运动对患者群体更令人担忧，而长期运动对患者群体益处更大。此外，这些高风险群体往往具有更复杂的特征，例如他们可能正在服用影响血栓形成途径的药物。因此，本综述重点关注了与患者群体中运动、身体活动和血栓形成相关的最新信息，并突出了该领域一些不断发展的领域。例如，热身运动的影响、药物的相互作用以及围绕运动的最佳量和强度的问题。
