Dalvie Mohamed Aqiel, Africa Algernon, Solomons Abdullah, London Leslie, Brouwer Derk, Kromhout Hans
Occupational and Environmental Health Research Unit, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
J Environ Sci Health B. 2009 Mar;44(3):271-7. doi: 10.1080/03601230902728351.
The study investigated serum endosulfan changes resulting from occupational exposure to the pesticide on farms. Eight applicators and 17 non-applicators were tested (serum endosulfan, anthropometry, short exposure questionnaire) before and after the first day of seasonal spraying. Task-based job exposure matrix (JEM) estimates were calculated. Mean baseline serum endosulfan (530 +/- 0.05 microg/L) was high. Increases in post-spraying endosulfan levels (IPSE) were higher in applicators (mean = 60 +/- 90 microg/L) than in non-applicators (mean = 3.5 x 10(- 6)+/- 90.0 microg/L) adjusting for age (beta = 54.0, p = 0.162, R(2) = 0.22). There was a weak positive relationship between IPSE and JEM estimates. IPSE occurred in applicators and non-applicators and were higher in applicators. The validity of the JEM weightings and characterization of other routes of pesticide exposure require further investigation.
该研究调查了农场中因职业接触农药硫丹而导致的血清硫丹变化情况。在季节性喷洒的第一天前后，对8名施药者和17名非施药者进行了测试（血清硫丹、人体测量、短期接触问卷）。计算了基于任务的工作接触矩阵（JEM）估计值。平均基线血清硫丹水平（530±0.05微克/升）较高。在调整年龄后，施药者喷洒后硫丹水平的增加量（IPSE）（平均值=60±90微克/升）高于非施药者（平均值=3.5×10⁻⁶±90.0微克/升）（β=54.0，p=0.162，R²=0.2）。IPSE与JEM估计值之间存在弱正相关关系。施药者和非施药者均出现了IPSE，且施药者的IPSE更高。JEM权重的有效性以及农药接触其他途径的特征需要进一步研究。
