Suppr超能文献

一种用于加速牙种植体周围组织中骨形成的电子装置。

An electronic device for accelerating bone formation in tissues surrounding a dental implant.

作者信息

Song Jong K, Cho Tae H, Pan Hui, Song Yoon M, Kim In S, Lee Tae H, Hwang Soon J, Kim Sung J

机构信息

School of Electrical Engineering and Computer Science, Seoul National University, Seoul, South Korea.

出版信息

Bioelectromagnetics. 2009 Jul;30(5):374-84. doi: 10.1002/bem.20482.

Abstract

A dental implant is a unique structure which can be used with a noninvasive method because it is inserted into the bone in part and extended extracorporally. This study presents an electronic device that is temporarily connected with the dental implant, and reports its effect on accelerating bone formation in the surrounding tissues in a canine mandibular model. A small sized and low power consumption biphasic electrical current (BEC) stimulator ASIC was developed and the surrounding tissue was exposed to continuous BEC stimulation for 7 days with the parameters of 20 microA/cm(2), 125 micros duration, and 100 pulses/s. After 2 (n = 5) and 5 weeks (n = 5), animals were sacrificed and the specimens were histomorphometrically evaluated. The newly formed bone area (BA) was 1.30 times (3 weeks, P < 0.05) and 1.35 times (5 weeks, P < 0.05) higher in the experimental group compared to the control group, respectively. Bone-implant contact (BIC) in 3-week specimens was 1.62 times (P < 0.05) greater in the experimental group, while there was no statistically significant difference in 5-week specimens. Based on these results showing accelerated bone formation on and around the dental implant, it could be suggested that the latent time for osseointegration in dental implants can be reduced, and the success rate of implants in poor quality bone can be increased by using our device with BEC.

摘要

牙种植体是一种独特的结构,因其部分植入骨内并向体外延伸,故可采用非侵入性方法使用。本研究展示了一种与牙种植体临时连接的电子设备,并报告了其在犬下颌模型中对加速周围组织骨形成的作用。开发了一种小尺寸、低功耗的双相电流(BEC)刺激器专用集成电路,并以20微安/平方厘米、125微秒持续时间和100脉冲/秒的参数对周围组织进行了7天的连续BEC刺激。在2周(n = 5)和5周(n = 5)后,处死动物并对标本进行组织形态计量学评估。与对照组相比,实验组新形成的骨面积(BA)在3周时分别高出1.30倍(P < 0.05),在5周时高出1.35倍(P < 0.05)。实验组3周标本中的骨-种植体接触(BIC)比对照组大1.62倍(P < 0.05),而5周标本中无统计学显著差异。基于这些显示牙种植体及其周围骨形成加速的结果,可以认为使用我们的BEC设备可以缩短牙种植体骨结合的潜伏时间,并提高在骨质较差情况下种植体的成功率。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验