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[冠心病患者传统危险因素的患病率]

[Prevalence of conventional risk factors in patients with coronary heart disease].

作者信息

Rinkūniene Egidija, Petrulioniene Zaneta, Laucevicius Aleksandras, Ringailaite Ernesta, Laucyte Agne

机构信息

Center of Cardiology and Angiology, Clinics of Santariskes, Vilnius University Hospital, Santariskiu g. 2, 08661 Vilnius, Lithuania.

出版信息

Medicina (Kaunas). 2009;45(2):140-6.

Abstract

Extensive clinical and statistical studies have identified risk factors that increase the incidence of coronary heart disease. It is commonly suggested that more than 50% of patients with coronary heart disease lack any of the conventional risk factors. OBJECTIVE. To determine the prevalence of four conventional risk factors among patients with coronary heart disease. MATERIAL AND METHODS. We analyzed data of 606 patients with coronary heart disease (myocardial infarction, unstable and stable angina pectoris) hospitalized in the Clinics of Santariskes, Vilnius University Hospital, in 1997-2005. RESULTS. Among patients with coronary heart disease, at least one of four conventional risk factors was present in 98% of patients. Hypertension was present in 47.7% of patients, diabetes - in 12.9%, dyslipidemia - 90.1%, and smoking - in 24.1% of patients. In younger patients (<55 years), only 2.3% of patients lacked any of four conventional risk factors. Two-thirds (66.5%) of younger patients with coronary heart disease had two and more risk factors. CONCLUSIONS. Considering the fact that patients with coronary heart disease often lack conventional risk factors, currently more attention is given to nontraditional risk factors as well as genetic causes of coronary heart disease. Nevertheless, the present study revealed that 98% of patients with coronary heart disease had at least one of four conventional risk factors. Among younger patients (younger than 55 years), conventional risk factors are identified very frequently. Thus, it can be concluded that in order to reduce the epidemic of coronary heart disease, much greater emphasis should be given to identify and to improve prevention of four conventional risk factors as well as the lifestyle of the patient.

摘要

广泛的临床和统计研究已确定了增加冠心病发病率的风险因素。通常认为,超过50%的冠心病患者没有任何传统风险因素。目的:确定冠心病患者中四种传统风险因素的患病率。材料与方法:我们分析了1997年至2005年在维尔纽斯大学医院桑塔里斯克斯诊所住院的606例冠心病患者(心肌梗死、不稳定型和稳定型心绞痛)的数据。结果:在冠心病患者中,98%的患者存在四种传统风险因素中的至少一种。高血压患者占47.7%,糖尿病患者占12.9%,血脂异常患者占90.1%,吸烟患者占24.1%。在年轻患者(<55岁)中,只有2.3%的患者没有四种传统风险因素中的任何一种。三分之二(66.5%)的年轻冠心病患者有两种及以上风险因素。结论:鉴于冠心病患者常常缺乏传统风险因素这一事实,目前对非传统风险因素以及冠心病的遗传病因也给予了更多关注。然而,本研究显示,98%的冠心病患者存在四种传统风险因素中的至少一种。在年轻患者(55岁以下)中,传统风险因素的检出率非常高。因此,可以得出结论,为了降低冠心病的流行程度,应更加重视识别和改善对四种传统风险因素以及患者生活方式的预防。

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