Haworth Jo, Young Carolyn, Thornton Everard
Walton Centre for Neurology and Neurosurgery, Liverpool.
Clin Rehabil. 2009 Apr;23(4):371-83. doi: 10.1177/0269215508101728.
To evaluate the effects of an exercise and education programme on primary outcomes of exercise efficacy and activity levels; and on secondary outcomes including quality of life, mood and physical disability.
Randomized, single blind trial.
Specialist neurosciences centre.
Forty-four patients with acquired neurological pathologies.
Twenty-one participants undertook a four-week exercise and education programme alongside standard follow-up care. Twenty-three participants underwent standard follow-up care alone.
Primary outcome measures included the Exercise Efficacy Scale and Human Activity Profile. Secondary outcomes were evaluated by the Short Form 36 Health Survey, Hospital Anxiety and Depression Scale, UWIST Mood Adjective Checklist, Motricity Index, Frenchay Arm Test, Rivermead Mobility Index, 10-metre timed walk and a visual analogue scale. Data were collected at baseline and at 6, 12 and 24 weeks.
At six weeks, significant improvements in exercise efficacy were found following the treatment but not the control (P= 0.001). Moderate improvements in activity levels were noted for both study groups with no between-group differences. Short Form 36 'physical health' and 'general health' domains showed trends towards increased positive change following the intervention, but these did not reach significant levels. Mood, physical impairment and physical disability remained unchanged within either study group. Longer term follow-up revealed that the improvements noted in exercise self-efficacy, activity levels and quality of life were maintained.
The intervention resulted in improved exercise efficacy and may positively influence the physical and general health dimensions of health-related quality of life.
评估一项运动与教育计划对运动效能和活动水平等主要结局;以及对包括生活质量、情绪和身体残疾在内的次要结局的影响。
随机单盲试验。
专业神经科学中心。
44例获得性神经疾病患者。
21名参与者在接受标准随访护理的同时,参加了为期四周的运动与教育计划。23名参与者仅接受标准随访护理。
主要结局指标包括运动效能量表和人类活动概况。次要结局通过简明健康调查问卷36项、医院焦虑抑郁量表、UWIST情绪形容词检查表、运动能力指数、弗伦奇手臂测试、里弗米德活动指数、10米定时步行和视觉模拟量表进行评估。在基线以及第6、12和24周收集数据。
在六周时,治疗组的运动效能有显著改善,而对照组没有(P = 0.001)。两个研究组的活动水平均有适度改善,组间无差异。干预后,简明健康调查问卷36项的“身体健康”和“总体健康”领域显示出积极变化增加的趋势,但未达到显著水平。两个研究组内的情绪、身体损伤和身体残疾均保持不变。长期随访显示,运动自我效能、活动水平和生活质量的改善得以维持。
该干预措施提高了运动效能,并可能对健康相关生活质量的身体和总体健康维度产生积极影响。