Department of Gynaecology, Herning Hospital, Denmark.
Arch Gynecol Obstet. 2009 Dec;280(6):911-6. doi: 10.1007/s00404-009-0989-0. Epub 2009 Mar 18.
Long-term follow-up 11 years after endometrial ablation.
A questionnaire on menstruation, hormone treatment, and operations on women, which had 421 endometrial ablations during 1990-1996, was added to registered data on cancer, operational and obstetrical history.
Eighty-two percent of the questionnaires were returned and answered. Of those women on hormone treatment after ablation 26% had a hysterectomy later on compared to 34% of women with no hormone treatment after ablation (P = 0.28; chi (2) test). Hysterectomy was directly proportional to the amount of meno/metrorrhagia; however, the number of women with a hysterectomy was evenly distributed in relation to the duration of hormone treatment. The time of hormone treatment in relation to the ablation was not associated with the distribution of meno/metrorrhagia or whether the women had a hysterectomy later on. We observed three women with incidental endometrial cancer at follow-up and the expected numbers were 6.8 cases.
Endometrial ablation is an effective form of treatment for menorrhagia with no increase in the incidence of endometrial cancer. Hormonal treatment does not seem to have any influence on the course of events.
子宫内膜消融术后 11 年的长期随访。
对 1990 年至 1996 年间进行的 421 例子宫内膜消融术的妇女进行了一项关于月经、激素治疗和手术的问卷调查，并将其添加到癌症、手术和产科病史的登记数据中。
82%的问卷被收回并回答。与未接受消融后激素治疗的妇女（34%）相比，接受消融后激素治疗的妇女中有 26%随后行子宫切除术（P=0.28；卡方检验）。子宫切除术与绝经/月经过多的量成正比；然而，行子宫切除术的妇女数量与激素治疗的持续时间均匀分布。激素治疗与消融的时间与绝经/月经过多的分布或妇女随后是否行子宫切除术无关。我们在随访中观察到 3 例偶发性子宫内膜癌，预期病例数为 6.8 例。
子宫内膜消融术是治疗月经过多的有效方法，不会增加子宫内膜癌的发病率。激素治疗似乎对病情没有影响。
