番樱桃属植物精油的化学成分及抗菌活性
Chemical composition and antibacterial activity of essential oils of Eugenia species.
作者信息
Magina Michele D A, Dalmarco Eduardo M, Wisniewski Alberto, Simionatto Edesio L, Dalmarco Juliana B, Pizzolatti Moacir G, Brighente Inês M C
机构信息
Departamento de Ciências Farmacêuticas, Universidade Regional de Blumenau, Blumenau, SC, 89.010-971, Brazil.
出版信息
J Nat Med. 2009 Jul;63(3):345-50. doi: 10.1007/s11418-009-0329-5. Epub 2009 Mar 24.
The essential oils of the leaves of Eugenia brasiliensis, Eugenia beaurepaireana, and Eugenia umbelliflora were analyzed by GC-MS. The major compounds found in the oil of E. brasiliensis were spathulenol (12.6%) and tau-cadinol (8.7%), of E. beaurepaireana were beta-caryophyllene (8.0%) and bicyclogermacrene (7.2%), and of E. umbelliflora were viridiflorol (17.7%) and beta-pinene (13.2%). These oils were assayed to determine their antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. All of the oils analyzed showed antibacterial activity, ranging from moderate to strong, which was most accentuated for the E. umbelliflora and E. brasiliensis oils, which strongly inhibited the growth of S. aureus giving values of MIC = 119.2 and 156.2 microg/mL, respectively.
采用气相色谱-质谱联用（GC-MS）技术对巴西番樱桃（Eugenia brasiliensis）、博勒番樱桃（Eugenia beaurepaireana）和伞花番樱桃（Eugenia umbelliflora）叶片的精油进行了分析。在巴西番樱桃精油中发现的主要化合物是匙叶桉油烯醇（12.6%）和τ-杜松醇（8.7%），在博勒番樱桃精油中是β-石竹烯（8.0%）和双环大根香叶烯（7.2%），在伞花番樱桃精油中是绿花白千层醇（17.7%）和β-蒎烯（13.2%）。对这些精油进行了测定，以确定它们对金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌的抗菌活性。所有分析的精油均表现出抗菌活性，范围从中度到强度，其中伞花番樱桃和巴西番樱桃精油的抗菌活性最为显著，它们对金黄色葡萄球菌的生长有强烈抑制作用，最低抑菌浓度（MIC）值分别为119.2和156.2微克/毫升。
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