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基于无标记分子开关的DNA杂交荧光分析:利用碳纳米管降低背景信号并提高特异性

Fluorescent assay of DNA hybridization with label-free molecular switch: reducing background-signal and improving specificity by using carbon nanotubes.

作者信息

Liu Yue, Wang Yongxiang, Jin Jianyu, Wang Hao, Yang Ronghua, Tan Weihong

机构信息

Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

出版信息

Chem Commun (Camb). 2009 Feb 14(6):665-7. doi: 10.1039/b819526a. Epub 2009 Jan 7.

DOI:10.1039/b819526a
PMID:19322415
Abstract

Using classic DNA-intercalating dye and carbon nanotubes, a simple, but efficient, method for fluorescent detection of DNA hybridization has been developed.

摘要

利用经典的DNA嵌入染料和碳纳米管,已开发出一种简单但高效的DNA杂交荧光检测方法。

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