测定巴西圣保罗东北地区花生制品中的黄曲霉毒素。
Determination of aflatoxins in peanut products in the northeast region of São Paulo, Brazil.
机构信息
Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil.
Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
出版信息
Int J Mol Sci. 2009 Jan;10(1):174-183. doi: 10.3390/ijms10010174. Epub 2009 Jan 6.
The aim of the present study was to determine aflatoxin levels in peanut products traded in the Northeast region of São Paulo, Brazil. To this end, 240 samples of peanut products traded in the cities of Araras, Leme, Pirassununga and Porto Ferreira were collected from June 2006 to May 2007. The samples were analyzed for aflatoxins (AF) B(1), B(2), G(1) and G(2) by high performance liquid chromatography. Results showed 44.2% samples positive for AF at levels of 0.5 to 103.8 microg x kg(-1). Nine of the positive samples (3.7% of the analysed samples) had total aflatoxin concentrations (B(1)+B(2)+G(1)+G(2)) higher than the limit established by Brazilian regulations (20 microg x kg(-1)). Based on the above data, the probable mean daily intake (PDI(M)) of aflatoxins from peanut products in the Northeast region of São Paulo was estimated to be 0.23 ng kg b.w. day(-1). Although this PDI(M) value was relatively low, results indicate that aflatoxin contamination of peanut products may be a public health concern in Brazil, when considering the potential exposure of highly susceptible consumers. For example, it should be emphasized that children are potentially exposed to aflatoxins, since they consume large quantities of peanut candies, and these products had the highest number of samples positive for AFB(1).
本研究旨在测定巴西圣保罗州东北部地区交易的花生产品中的黄曲霉毒素水平。为此，于 2006 年 6 月至 2007 年 5 月间采集了来自阿雷拉斯、莱梅、皮拉西翁嫩塞和波图费雷拉等城市交易的 240 份花生产品样本。通过高效液相色谱法对这些样本中的黄曲霉毒素（AF）B(1)、B(2)、G(1)和 G(2)进行了分析。结果显示，44.2%的样本呈阳性，其黄曲霉毒素含量在 0.5 至 103.8 µg x kg(-1)之间。在呈阳性的样本中，有 9 个样本（占分析样本的 3.7%）的总黄曲霉毒素浓度（B(1)+B(2)+G(1)+G(2)）超过了巴西法规规定的限值（20 µg x kg(-1)）。根据上述数据，估计来自圣保罗州东北部地区花生产品的黄曲霉毒素的可能平均日摄入量（PDI(M)）为 0.23 ng kg b.w. day(-1)。尽管这个 PDI(M)值相对较低，但结果表明，考虑到高度易感消费者的潜在暴露风险，花生产品的黄曲霉毒素污染可能是巴西的一个公共卫生关注点。例如，应当强调的是，儿童可能会接触到黄曲霉毒素，因为他们会大量食用花生糖，而这些产品中呈 AFB(1)阳性的样本数量最多。
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