Peeling Peter, Dawson Brian, Goodman Carmel, Landers Grant, Wiegerinck Erwin T, Swinkels Dorine W, Trinder Debbie
School of Sport Science, Exercise and Health, The University of Western Australia, Western Australia, Australia.
Med Sci Sports Exerc. 2009 May;41(5):1138-45. doi: 10.1249/MSS.0b013e318192ce58.
This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running.
Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75%-80% peak VO2 running velocity, and a 10 x 1-km interval running session (INT) at 90%-95% of the peak VO2 running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression.
After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P < 0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P < 0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P < 0.05) but were not different between trials.
Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.
本研究评估了跑步过程中训练强度和地面类型对溶血、炎症和铁调素活性的影响。
10名训练有素的男性耐力运动员完成了一项分级运动测试，在草地（GRASS）和柏油路面（ROAD）上以75%-80%的峰值摄氧量跑步速度进行了两次连续10公里的跑步，以及一次在90%-95%的峰值摄氧量跑步速度下进行的10×1公里间歇跑步训练（INT）。在运动前、运动后即刻、运动后3小时和24小时采集静脉血和尿液样本。分析血清样本中白细胞介素-6（IL-6）、游离血红蛋白（Hb）、触珠蛋白（Hp）、铁和铁蛋白的循环水平。分析尿液样本中铁调素表达的变化。
跑步后，在所有三种情况下，IL-6和游离Hb均显著高于运动前值，血清Hp显著低于运动前值（P<0.05）。此外，与GRASS组相比，INT组的IL-6水平和游离Hb相对于基线的变化显著更大（P<0.05）。GRASS和ROAD训练表面之间没有差异（P>0.05）。在所有三种情况下，运动后血清铁和铁蛋白均显著增加（P<0.05），但各试验之间没有差异。
更高的跑步强度会引发更多的炎症和溶血，但这些变量不受训练地面类型的影响。
