锝-99m 胱氨酸与锝-99m 巯基乙酰三甘氨酸在正常人和肾功能损害患者中的比较评估。

Comparative evaluation of Tc-99m cystine and Tc-99m MAG3 in normals and patients with renal functional impairment.

作者信息

Misra Mridula, Pradhan Prasanta K, De Kakali, Chandra Susmita, Das Birendra K

机构信息

Nuclear Medicine Division, Indian Institute of Chemical Biology, Kolkata, West Bengal, India.

出版信息

Clin Nucl Med. 2009 Mar;34(3):141-5. doi: 10.1097/RLU.0b013e3181966db3.

DOI:10.1097/RLU.0b013e3181966db3

PMID:19352274

Abstract

Tc-99m cystine has been proved to be a good renal agent in animals for morphologic as well as the functional status of the kidney. In this study, we compared Tc-99m cystine with Tc-99m mercaptoacetyltriglycine, which is used for evaluation of renal function in normal patients, and those with various degrees of renal functional impairment. The clearance values and static images are compared with Tc-99m mercaptoacetyltriglycine. The results show that Tc-99m cystine has good radiopharmaceutical characteristics suitable for evaluation of both renal function as well as morphology.

摘要

锝-99m 胱氨酸已被证明在动物体内是一种用于评估肾脏形态学和功能状态的良好肾脏显像剂。在本研究中，我们将锝-99m 胱氨酸与用于评估正常患者及不同程度肾功能损害患者肾功能的锝-99m 巯基乙酰三甘氨酸进行了比较。将清除率值和静态图像与锝-99m 巯基乙酰三甘氨酸进行比较。结果表明，锝-99m 胱氨酸具有良好的放射性药物特性，适用于评估肾功能和形态学。