Taga Ibrahim, Oumbe Valere Aime Soh, Johns Robert, Zaidi Mohsin Abbas, Yonkeu Jeanne Ngogang, Altosaar Illimar
Clinical Biochemistry and Nutrition Unit, Biochemistry Dept, Faculty of Sciences, PO Box 24157 Dla, University of Douala, Cameroon.
Afr Health Sci. 2008 Sep;8(3):180-5.
Hypothyroidism in utero leading to mental retardation is highly prevalent in developing countries where iodine deficiency and thiocyanate overload are combined.
To explore prevalence of IDD in Bamougoum, a mountain region of western Cameroon, by studying urinary iodine and thiocyanate excretion levels in children.
Bamougoum district in western Cameroon was selected for closer study due to its geographic location predisposing to iodine deficiency disorders (IDD). A comprehensive sampling strategy included 24-h urine samples collected over three days from 120 school-aged children. Urinary iodine and thiocyanate levels were measured by colorimetric methods.
Twenty one percent of boys between the ages 3 and 19 were classified as iodine deficient. The prevalence of thiocyanate overload in the same population was found to be 20%.
Presence of endemic iodine deficiency and excessive thiocyanate in the population indicates that the region is at risk of iodine deficiency disorder. A multifactorial approach that includes improvement of diet, increasing iodine and minimizing goitrogen substances intake, soil and crop improvement and an iodine supplementation program may help alleviate IDD in the affected area studied.
在碘缺乏与硫氰酸盐过量并存的发展中国家,子宫内甲状腺功能减退导致智力发育迟缓的情况极为普遍。
通过研究儿童尿碘和硫氰酸盐排泄水平,探讨喀麦隆西部山区巴穆古姆的碘缺乏病(IDD)患病率。
由于喀麦隆西部的巴穆古姆地区地理位置易导致碘缺乏病(IDD),故选择该地区进行深入研究。采用全面的抽样策略,从120名学龄儿童中连续三天收集24小时尿样。采用比色法测定尿碘和硫氰酸盐水平。
3至19岁男孩中有21%被归类为碘缺乏。同一人群中硫氰酸盐过量的患病率为20%。
人群中存在地方性碘缺乏和硫氰酸盐过量表明该地区存在碘缺乏病风险。包括改善饮食、增加碘摄入量、减少致甲状腺肿物质摄入、改良土壤和作物以及实施碘补充计划在内的多因素方法,可能有助于减轻所研究的受影响地区的碘缺乏病。