Cashman Clodagh M, Ruotsalainen Jani H, Greiner Birgit A, Beirne Paul V, Verbeek Jos H
Research Department, Medical Council, Lynn House Lower Rathmines Road, Dublin, Ireland, 6.
Cochrane Database Syst Rev. 2009 Apr 15;2009(2):CD006566. doi: 10.1002/14651858.CD006566.pub2.
Workforce alcohol and drug testing is commonplace but its effect in reducing occupational injuries remains unclear.
To assess the effects of alcohol and drug screening of occupational drivers (operating a motorised vehicle) in preventing injury or work-related effects such as sickness absence related to injury.
We searched the following databases up to June 2007 (or up to the latest issue then available): MEDLINE, EMBASE, The Cochrane Library, Cochrane Occupational Health Field's specialised register, DARE, PsychINFO, ERIC, ETOH, CISDOC, NIOSHTIC, TRANSPORT, Zetoc, Science Citation Index and Social Science Citation index and HSELINE. We also searched reference lists, relevant websites and conducted hand searching.
Randomised controlled trials (RCTs), cluster-randomised trials, controlled clinical trials, controlled before and after studies (more than three time points to be measured before and after the study) and interrupted time-series (ITS) studies that evaluated alcohol or drug screening interventions for occupational drivers (compared to another intervention or no intervention) with an outcome measured as a reduction in injury or a proxy measure thereof.
Two review authors independently extracted data and assessed study quality. We contacted authors of the included studies for further information.
We included two interrupted time-series studies conducted in the USA. One study was conducted in five large US transportation companies (N = 115,019) that carried passengers and/or cargo. Monthly injury rates were available from 1983 to 1999. In the study company, two interventions of interest were evaluated: mandatory random drug testing and mandatory random and for-cause alcohol testing programmes. The third study focused only on mandatory random drug testing and was conducted on federal injury data that covered all truck drivers of interstate carriers.We recalculated the results from raw data provided by the study authors. Following reanalysis, we found that in one study mandatory random and for-cause alcohol testing was associated with a significant decrease in the level of injuries immediately following the intervention (-1.25 injuries/100 person years, 95% CI -2.29 to -0.21) but did not significantly affect the existing long-term downward trend (-0.28 injuries/100 person years/year, 95% CI -0.78 to 0.21).Mandatory random drug testing was significantly associated with an immediate change in injury level following the intervention (1.26 injuries/100 person years, 95% CI 0.36 to 2.16) in one study, and in the second study there was no significant effect (-1.36/injuries/100 person years, 95% CI -1.69 to 0.41). In the long term, random drug testing was associated with a significant increase in the downward trend (-0.19 injuries/100 person years/year, 95% CI -0.30 to -0.07) in one study, the other study was also associated with a significant improvement in the long-term downward trend (-0.83 fatal accidents/100 million vehicle miles/year, 95% CI -1.08 to -0.58).
AUTHORS' CONCLUSIONS: There is insufficient evidence to advise for or against the use of drug and alcohol testing of occupational drivers for preventing injuries as a sole, effective, long-term solution in the context of workplace culture, peer interaction and other local factors. Cluster-randomised trials are needed to better address the effects of interventions for injury prevention in this occupational setting.
对员工进行酒精和药物检测很常见,但它在减少职业伤害方面的效果仍不明确。
评估对职业驾驶员(驾驶机动车辆)进行酒精和药物筛查在预防伤害或与工作相关的影响(如因伤缺勤)方面的效果。
我们检索了以下数据库至2007年6月(或至当时最新的期次):MEDLINE、EMBASE、Cochrane图书馆、Cochrane职业健康领域专业注册库、DARE、PsychINFO、ERIC、ETOH、CISDOC、NIOSHTIC、TRANSPORT、Zetoc、科学引文索引和社会科学引文索引以及HSELINE。我们还检索了参考文献列表、相关网站并进行了手工检索。
随机对照试验(RCT)、整群随机试验、对照临床试验、前后对照研究(研究前后需测量三个以上时间点)以及中断时间序列(ITS)研究,这些研究评估了针对职业驾驶员的酒精或药物筛查干预措施(与另一干预措施或不干预相比),其结果以伤害减少或替代指标来衡量。
两位综述作者独立提取数据并评估研究质量。我们联系了纳入研究的作者以获取更多信息。
我们纳入了两项在美国进行的中断时间序列研究。一项研究在美国五家大型运输公司(N = 115,019)中进行,这些公司运送乘客和/或货物。可获取1983年至1999年的月度伤害率。在研究公司中,评估了两项相关干预措施:强制性随机药物检测和强制性随机及因由酒精检测计划。第三项研究仅关注强制性随机药物检测,基于涵盖所有州际运输公司卡车司机的联邦伤害数据进行。我们根据研究作者提供的原始数据重新计算了结果。重新分析后,我们发现一项研究中,强制性随机及因由酒精检测与干预后立即出现的伤害水平显著下降相关(-1.25起伤害/100人年,95%可信区间 -2.29至 -0.21),但未显著影响现有的长期下降趋势(-0.28起伤害/100人年/年,95%可信区间 -0.78至0.21)。在一项研究中,强制性随机药物检测与干预后伤害水平的立即变化显著相关(1.26起伤害/100人年,95%可信区间0.36至2.16),而在第二项研究中无显著影响(-1.36起伤害/100人年,95%可信区间 -1.69至0.41)。从长期来看,一项研究中随机药物检测与下降趋势的显著增加相关(-0.19起伤害/100人年/年,95%可信区间 -0.30至 -0.07),另一项研究也与长期下降趋势的显著改善相关(-0.83起致命事故/1亿车英里/年,95%可信区间 -1.08至 -0.58)。
在工作场所文化、同伴互动和其他当地因素的背景下,没有足够的证据建议支持或反对将对职业驾驶员进行药物和酒精检测作为预防伤害的唯一、有效、长期解决方案。需要进行整群随机试验,以更好地探讨在这种职业环境中预防伤害干预措施的效果。