Brant Angela M, Haberstick Brett C, Corley Robin P, Wadsworth Sally J, DeFries John C, Hewitt John K
Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309-0447, USA.
Behav Genet. 2009 Jul;39(4):393-405. doi: 10.1007/s10519-009-9268-x. Epub 2009 Apr 18.
The genetic and environmental trends in IQ development were assessed in 483 same-sex twin pairs in the Colorado longitudinal twin study using maximum-likelihood model-fitting analysis. The twins were assessed periodically from ages 1 to 16. Results show a decreasing influence of shared environment and an increasing influence of heritability across development, with large and increasing age to age stability of genetic influences. Non-shared environment contributes almost exclusively to age to age change. Similar analyses were conducted designating the top 15% of the sample as having high IQ at each age. The developmental etiology of high IQ did not significantly differ from that found for the continuous measure in this relatively novel analysis. These results demonstrate early stability in etiological influences on IQ and have potential implications for gene-finding efforts, suggesting that samples selected for high IQ can be used to find genetic variation that will be applicable to the full range of the IQ distribution, although conclusive demonstration that the same genes are indeed involved was beyond the scope of this study.
在科罗拉多纵向双胞胎研究中,运用最大似然模型拟合分析,对483对同性双胞胎的智商发展中的遗传和环境趋势进行了评估。这些双胞胎从1岁到16岁期间接受定期评估。结果显示,在整个发展过程中,共享环境的影响逐渐减少,遗传力的影响逐渐增加,且遗传影响的年龄稳定性大且不断增强。非共享环境几乎完全导致了年龄之间的变化。在每个年龄将样本中智商最高的15%指定为高智商人群,进行了类似分析。在这项相对新颖的分析中,高智商的发展病因与连续测量的结果没有显著差异。这些结果表明,对智商的病因影响具有早期稳定性,对基因寻找工作具有潜在意义,这表明选择高智商样本可用于发现适用于整个智商分布范围的基因变异,尽管本研究的范围无法确凿证明确实涉及相同的基因。