Ozawa Nobuyoshi, Sumi Yasunori, Chong Changho, Kurabayashi Tohru
Division of Oral and Dental Surgery, Department of Advanced Medicine, National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Br J Oral Maxillofac Surg. 2009 Dec;47(8):622-6. doi: 10.1016/j.bjoms.2009.03.012. Epub 2009 Apr 23.
Optical coherence tomography (OCT) is a new method of biomedical imaging that can generate high-resolution, cross-sectional images of microstructures. The purpose of this study was to present the first OCT images of oral vascular anomalies using a new advanced OCT scanner that we have developed, and to discuss the application of our system for oral soft tissues. Knowledge of the size and area of the vascular structures can be useful for the diagnosis and choice of the best treatment. Before excision, oral vascular malformations were assessed by OCT in vivo. Histopathological sections were taken and compared with the OCT images to make clinicopathological correlations. OCT provided clear images of all the vascular lesions examined. Oval to roundish, signal-poor areas sharply demarcated by a surrounding signal-rich layer correlated well with the histopathological diagnosis. OCT images provide information about subsurface structure non-invasively that is otherwise obtainable only by examination of a biopsy specimen. The analysis of oral vascular lesions by OCT provides new insights into non-invasive diagnosis and can be helpful in the selection of the most appropriate treatment.
光学相干断层扫描（OCT）是一种新型生物医学成像方法，能够生成微观结构的高分辨率横断面图像。本研究的目的是使用我们研发的新型先进OCT扫描仪展示口腔血管异常的首批OCT图像，并探讨该系统在口腔软组织中的应用。了解血管结构的大小和面积有助于诊断及选择最佳治疗方案。在切除之前，通过OCT对口腔血管畸形进行活体评估。获取组织病理学切片并与OCT图像进行比较，以建立临床病理相关性。OCT为所有检查的血管病变提供了清晰图像。椭圆形至圆形、由周围信号丰富层清晰界定的信号贫乏区域与组织病理学诊断高度相关。OCT图像以非侵入性方式提供有关皮下结构的信息，否则只有通过检查活检标本才能获得这些信息。通过OCT分析口腔血管病变为非侵入性诊断提供了新的见解，并有助于选择最合适的治疗方法。
