Perez-Lloret Santiago, Rossi Malco, Nouzeilles María Inés, Trenkwalder Claudia, Cardinali Daniel P, Merello Marcelo
Movement Disorders Section, Raul Carrea Institute for Neurological Research, FLENI, Montañeses 2325 C1428AQK, Cdad Aut Buenos Aires, Argentina.
J Neurol. 2009 Sep;256(9):1480-4. doi: 10.1007/s00415-009-5141-3. Epub 2009 Apr 29.
The aim of this study was to compare the results of the day-to-day self-evaluation of sleep quality by sleep logs with Parkinson's disease sleep scale (PDSS) in Parkinson's disease (PD) patients. Actigraphy was used as an independent analysis of nighttime activity interfering with sleep. A total of 71 idiopathic PD patients and 21 age- and sex-matched normal individuals lacking any type of sleep disturbance were recruited. Sleep was evaluated by PDSS, 7-d sleep log and actigraphy. Sleep logs and PDSS showed reduced sleep quality and daytime somnolence scores in moderate/severe PD patients as compared to healthy controls. Significant correlations were found between sleep quality in sleep logs and all domains of PDSS sleep quality, except for the presence of nocturia, which correlated with nocturnal activity. PD severity and depression were the only predictors of reduced sleep quality. The retrospective and day-to-day sleep self-evaluations were coincident. Reduced sleep quality was related to increased PD severity and depression scores.
本研究的目的是比较帕金森病（PD）患者通过睡眠日志进行的日常睡眠质量自我评估结果与帕金森病睡眠量表（PDSS）的结果。活动记录仪被用作干扰睡眠的夜间活动的独立分析工具。共招募了71例特发性PD患者和21名年龄及性别匹配、无任何类型睡眠障碍的正常个体。通过PDSS、7天睡眠日志和活动记录仪对睡眠进行评估。与健康对照相比，中度/重度PD患者的睡眠日志和PDSS显示睡眠质量和日间嗜睡评分降低。除夜尿症与夜间活动相关外，睡眠日志中的睡眠质量与PDSS睡眠质量的所有领域之间均存在显著相关性。PD严重程度和抑郁是睡眠质量降低的唯一预测因素。回顾性和日常睡眠自我评估结果一致。睡眠质量降低与PD严重程度增加和抑郁评分升高有关。
