脾脏集落形成病毒的Friend毒株：一种小鼠C型亲嗜性病毒序列与异嗜性病毒相关序列之间的重组体。
Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus.
作者信息
Troxler D H, Boyars J K, Parks W P, Scolnick E M
出版信息
J Virol. 1977 May;22(2):361-72. doi: 10.1128/JVI.22.2.361-372.1977.
Abstract
The genome of the Friend strain of the spleen focus-forming virus (SFFV) has been analyzed by molecular hybridization. SFFV is composed of genetic sequences homologous to Friend type C helper virus (F-MuLV) and SFFV-specific sequences not present in F-MuLV. These SFFV-specific sequences are present in both the Friend and Rauscher strains of murine erythroleukemia virus. The SFFV-specific sequences are partially homologous to three separate strains of mouse xenotropic virus but not to several cloned mouse ecotropic viruses. Thus, the Friend strain of SFFV appears to be a recombinant between a portion of the F-MuLV genome and RNA sequences that are highly related to murine xenotropic viruses. The implications of the acquisition of the xenotropic virus-related sequences are discussed in relation to the leukemogenicity of SFFV, and a model for the pathogenicity of other murine leukemia-inducing viruses is proposed.
摘要
已通过分子杂交分析了脾集落形成病毒（SFFV）Friend株的基因组。SFFV由与Friend C型辅助病毒（F-MuLV）同源的遗传序列和F-MuLV中不存在的SFFV特异性序列组成。这些SFFV特异性序列存在于鼠红细胞白血病病毒的Friend株和Rauscher株中。SFFV特异性序列与三株不同的小鼠嗜异性病毒部分同源，但与几株克隆的小鼠亲嗜性病毒不同源。因此，SFFV的Friend株似乎是F-MuLV基因组的一部分与与小鼠嗜异性病毒高度相关的RNA序列之间的重组体。本文讨论了获得嗜异性病毒相关序列对SFFV致白血病性的影响，并提出了其他鼠白血病诱导病毒的致病模型。
相似文献
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Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus.脾脏集落形成病毒的Friend毒株：一种小鼠C型亲嗜性病毒序列与异嗜性病毒相关序列之间的重组体。
J Virol. 1977 May;22(2):361-72. doi: 10.1128/JVI.22.2.361-372.1977.
2
Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus.脾灶形成病毒的Friend毒株是嗜亲性鼠C型病毒与异嗜性C型病毒env基因区域之间的重组体。
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4671-5. doi: 10.1073/pnas.74.10.4671.
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Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: potential relationship to the origin of replication-defective spleen focus-forming virus.弗氏鼠C型病毒的辅助非依赖型貂细胞集落诱导株：与复制缺陷型脾集落形成病毒起源的潜在关系
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4
Presence and expression of Friend erythroleukemia virus-related sequences in normal and leukemic mouse tissues.正常和白血病小鼠组织中Friend红白血病病毒相关序列的存在与表达。
Proc Natl Acad Sci U S A. 1979 Sep;76(9):4455-9. doi: 10.1073/pnas.76.9.4455.
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Type-specific radioimmunoassays for the gp70s of mink cell focus-inducing murine leukemia viruses: expression of a cross-reacting antigen in cells infected with the Friend strain of the spleen focus-forming virus.水貂细胞集落诱导型小鼠白血病病毒gp70的型特异性放射免疫测定：脾脏集落形成病毒Friend株感染细胞中一种交叉反应抗原的表达
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6
Spleen focus-forming Friend virus: identification of genomic RNA and its relationship to helper virus RNA.脾脏灶形成性弗氏病毒：基因组RNA的鉴定及其与辅助病毒RNA的关系。
J Virol. 1979 Jul;31(1):133-46. doi: 10.1128/JVI.31.1.133-146.1979.
7
Cas spleen focus-forming virus. II. Further biological and biochemical characterization.卡斯脾灶形成病毒。II. 进一步的生物学和生化特性
J Virol. 1983 Aug;47(2):329-36. doi: 10.1128/JVI.47.2.329-336.1983.
8
Analysis of integrated proviral DNA sequences with an octadecanucleotide probe designed for specific identification of spleen focus-forming virus in the mouse genome.用为在小鼠基因组中特异性鉴定脾集落形成病毒而设计的十八核苷酸探针分析整合的前病毒DNA序列。
J Virol. 1986 Jan;57(1):349-52. doi: 10.1128/JVI.57.1.349-352.1986.
9
Sequence flexibility in the polytropic env gp70-derived region of the membrane glycoprotein (gp55) of Friend spleen focus-forming virus affects its biological activity.弗氏脾脏灶形成病毒膜糖蛋白（gp55）的多嗜性env gp70衍生区域中的序列灵活性影响其生物学活性。
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The detection of a spleen focus-forming virus neoantigen by lymphocyte-mediated cytolysis.通过淋巴细胞介导的细胞溶解检测脾灶形成病毒新抗原。
J Exp Med. 1978 Jul 1;148(1):18-31. doi: 10.1084/jem.148.1.18.
引用本文的文献
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A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.组成型激活的促红细胞生成素受体刺激增殖，并有助于多能、定向非红系和红系祖细胞的转化。
Mol Cell Biol. 1994 Apr;14(4):2266-77. doi: 10.1128/mcb.14.4.2266-2277.1994.
2
Plasma membrane glycoproteins encoded by cloned Rauscher and Friend spleen focus-forming viruses.由克隆的劳舍尔和弗瑞德脾脏集落形成病毒编码的质膜糖蛋白。
J Virol. 1980 Sep;35(3):844-53. doi: 10.1128/JVI.35.3.844-853.1980.
3
New cell surface gp70 related to Friend mink cell focus-inducing virus is expressed on Friend virus-induced erythroleukemic spleen cells after elimination of ecotropic Friend virus gp70 in Rfv-3r/s mice.与弗氏水貂细胞灶诱导病毒相关的新细胞表面糖蛋白70，在Rfv-3r/s小鼠中消除嗜异性弗氏病毒糖蛋白70后，表达于弗氏病毒诱导的红白血病脾细胞上。
J Exp Med. 1981 Sep 1;154(3):868-82. doi: 10.1084/jem.154.3.868.
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Spleen focus-forming virus: specific neutralization by antisera to certain gag gene-encoded proteins.脾灶形成病毒：针对某些 gag 基因编码蛋白的抗血清进行特异性中和作用。
J Virol. 1981 Jan;37(1):55-60. doi: 10.1128/JVI.37.1.55-60.1981.
5
Growth of factor-dependent hemopoietic precursor cell lines.因子依赖性造血前体细胞系的生长
J Exp Med. 1980 Oct 1;152(4):1036-47. doi: 10.1084/jem.152.4.1036.
6
Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation.编码脾集落形成病毒gp52蛋白的包膜基因序列是诱导红细胞增殖所必需的。
J Virol. 1982 Jul;43(1):223-33. doi: 10.1128/JVI.43.1.223-233.1982.
7
Friend disease in vitro.体外Friend病
J Exp Med. 1981 Sep 1;154(3):594-608. doi: 10.1084/jem.154.3.594.
8
Helper virus is not required for in vitro erythroid transformation of hematopoietic cells by Friend virus.弗氏病毒对造血细胞进行体外红系转化时无需辅助病毒。
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5287-91. doi: 10.1073/pnas.77.9.5287.
9
Anemia- and polycythemia-inducing isolates of Friend spleen focus-forming virus. Biological and molecular evidence for two distinct viral genomes.弗氏脾脏灶形成病毒的贫血和红细胞增多诱导分离株。两种不同病毒基因组的生物学和分子证据。
J Exp Med. 1980 Jun 1;151(6):1477-92. doi: 10.1084/jem.151.6.1477.
10
Immunoselection of mutants deficient in cell surface glycoproteins encoded by murine erythroleukemia viruses.对缺乏由鼠红细胞白血病病毒编码的细胞表面糖蛋白的突变体进行免疫选择。
Proc Natl Acad Sci U S A. 1980 Jan;77(1):57-61. doi: 10.1073/pnas.77.1.57.
本文引用的文献
1
A virus-induced disease of mice characterized by erythrocytopoiesis and lymphoid leukemia.一种由病毒引起的小鼠疾病，其特征为红细胞生成和淋巴白血病。
J Natl Cancer Inst. 1962 Sep;29:515-43.
2
AN UNIDENTIFIED VIRUS WHICH CAUSES THE RAPID PRODUCTION OF TUMOURS IN MICE.一种能在小鼠体内迅速引发肿瘤的未识别病毒。
Nature. 1964 Dec 12;204:1104-5. doi: 10.1038/2041104b0.
3
Leukemogenic activity of filtrates from radiation-induced lymphoid tumors of mice.小鼠辐射诱导淋巴肿瘤滤液的致白血病活性。
Science. 1959 Aug 14;130(3372):387-8. doi: 10.1126/science.130.3372.387.
4
Cell-free transmission in adult Swiss mice of a disease having the character of a leukemia.具有白血病特征的疾病在成年瑞士小鼠中的无细胞传播。
J Exp Med. 1957 Apr 1;105(4):307-18. doi: 10.1084/jem.105.4.307.
5
Separation of murine cellular and murine leukaemia virus DNA polymerases.小鼠细胞和小鼠白血病病毒DNA聚合酶的分离
Nat New Biol. 1971 Jun 9;231(23):163-7. doi: 10.1038/newbio231163a0.
6
Ribonucleic acid isolated by cesium chloride centrifugation.通过氯化铯离心法分离得到的核糖核酸。
Biochemistry. 1974 Jun 4;13(12):2633-7. doi: 10.1021/bi00709a025.
7
B-tropic Friend virus: a host-range pseudotype of spleen focus-forming virus (SFFV).B嗜异性Friend病毒：脾脏灶形成病毒（SFFV）的宿主范围假型。
Virology. 1973 Oct;55(2):363-70. doi: 10.1016/0042-6822(73)90176-1.
8
Kinetic complexity of RNA molecules.RNA分子的动力学复杂性。
J Mol Biol. 1972 Jan 14;63(1):21-39. doi: 10.1016/0022-2836(72)90519-0.
9
Radioimmunoassay of mammalian type-C viral proteins: interspecies antigenic reactivities of the major internal polypeptide.哺乳动物C型病毒蛋白的放射免疫测定：主要内部多肽的种间抗原反应性
Proc Natl Acad Sci U S A. 1972 Jul;69(7):1766-70. doi: 10.1073/pnas.69.7.1766.
10
Evolution of C-type viral genes: inheritance of exogenously acquired viral genes.C型病毒基因的进化：外源获得的病毒基因的遗传。
Nature. 1974 Dec 6;252(5483):456-9. doi: 10.1038/252456a0.
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