Haider Bilal, McCormick David A
Department of Neurobiology, Kavli Institute for Neuroscience, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
Neuron. 2009 Apr 30;62(2):171-89. doi: 10.1016/j.neuron.2009.04.008.
The highly interconnected local and large-scale networks of the neocortical sheet rapidly and dynamically modulate their functional connectivity according to behavioral demands. This basic operating principle of the neocortex is mediated by the continuously changing flow of excitatory and inhibitory synaptic barrages that not only control participation of neurons in networks but also define the networks themselves. The rapid control of neuronal responsiveness via synaptic bombardment is a fundamental property of cortical dynamics that may provide the basis of diverse behaviors, including sensory perception, motor integration, working memory, and attention.
新皮质层高度互联的局部和大规模网络会根据行为需求快速且动态地调节其功能连接性。新皮质的这一基本运作原理由兴奋性和抑制性突触传入的持续变化流介导，这些传入不仅控制神经元在网络中的参与，还定义了网络本身。通过突触轰击对神经元反应性的快速控制是皮质动力学的一项基本特性，可能为包括感觉知觉、运动整合、工作记忆和注意力在内的多种行为提供基础。
