蒲桃和马蒂乌斯山香薷的体外光毒性活性

In vitro phototoxic activity of Eugenia jambolana L. and Hyptis martiusii Benth.

作者信息

Coutinho Henrique D M, Costa José G M, Lima Edeltrudes O, Siqueira-Júnior José P

机构信息

Laboratory of Research in Natural Products, Center of Biological Sciences and Health, University of the Region of Cariri, Crato (CE), Brazil.

出版信息

J Photochem Photobiol B. 2009 Jul 17;96(1):63-5. doi: 10.1016/j.jphotobiol.2009.04.002. Epub 2009 Apr 12.

DOI:10.1016/j.jphotobiol.2009.04.002

PMID:19409807

Abstract

Ethanol extracts from Hyptis martiusii and Eugenia jambolana were assayed for light-mediated activity against strains of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Duplicate assays were conducted with and without exposure to UV-A radiation to test for light-activated or light-enhanced activity. Both extracts showed activity against at least two bacterial strains, but H. martiusii was the most active extract, being active against all strains of S. aureus and E. coli. The results represent a first report of the light-mediated antimicrobial activities of H. martiusii and E. jambolana and suggest that phytochemical investigations may be warranted.

摘要

对来自马蒂乌斯山香茶菜（Hyptis martiusii）和乌墨（Eugenia jambolana）的乙醇提取物进行了检测，以评估其对金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌菌株的光介导活性。在有和没有暴露于UV-A辐射的情况下进行了重复检测，以测试光激活或光增强活性。两种提取物都对至少两种细菌菌株显示出活性，但马蒂乌斯山香茶菜提取物是活性最强的提取物，对所有金黄色葡萄球菌和大肠杆菌菌株都有活性。这些结果首次报道了马蒂乌斯山香茶菜和乌墨的光介导抗菌活性，并表明可能有必要进行植物化学研究。