Bejenaru Paula Luiza, Popescu Bogdan, Oancea Alina Lavinia Antoaneta, Simion-Antonie Catrinel Beatrice, Berteșteanu Gloria Simona, Condeescu-Cojocarița Mihnea, Cîrstea Anca Ionela, Oașă Irina Doinița, Schipor-Diaconu Teodora Elena, Popescu Dan, Grigore Raluca
Department 12-Otorhynolaryngology, Ophthalmology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Otorhinolaryngology Department, "Colțea" Clinical Hospital, 030171 Bucharest, Romania.
J Clin Med. 2022 Aug 19;11(16):4875. doi: 10.3390/jcm11164875.
Squamous cell carcinoma of the head and neck (HNSCC) is a common malignancy often diagnosed in the advanced stage with a complex negative influence on the patient's quality of life (QoL). Given its multi-modal treatment, the first step is to adequately balance the needs of the patient, and the second step includes the consultations, interventions, and care provided by the medical team, with the purpose of improving the overall management of the HNSCC. Current attempts to develop and validate quality-of-life instruments specific to cancers of the head and neck have been reported, and certain questionnaires are now available. We performed a retrospective study in a tertiary centre, involving 89 patients who survived 3 years after HNSCC surgery. A patient-related outcome measurement was made using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-H&N35 instruments to assess QoL at admission and 3 years after treatment. The 3-year survivors reported an overall improvement in QoL compared with those in the pre-treatment period. The unique details of head and neck cancer treatments outline the importance of considering the characteristics of the patient population in quality-of-life research and also identify how quality-of-life data can contribute to the care provided by the multi-disciplinary team involved in a patient's follow-up.
头颈部鳞状细胞癌(HNSCC)是一种常见的恶性肿瘤,通常在晚期被诊断出来,对患者的生活质量(QoL)有复杂的负面影响。鉴于其多模式治疗,第一步是充分平衡患者的需求,第二步包括医疗团队提供的咨询、干预和护理,目的是改善HNSCC的整体管理。目前已经报道了开发和验证头颈部癌症特异性生活质量工具的尝试,现在有一些问卷可供使用。我们在一家三级中心进行了一项回顾性研究,纳入了89例HNSCC手术后存活3年的患者。使用欧洲癌症研究与治疗组织(EORTC)QLQ-C30和QLQ-H&N35工具进行患者相关结局测量,以评估入院时和治疗后3年的生活质量。与治疗前相比,3年幸存者报告生活质量总体有所改善。头颈部癌症治疗的独特细节凸显了在生活质量研究中考虑患者群体特征的重要性,也确定了生活质量数据如何有助于参与患者随访的多学科团队提供的护理。