Schiffman Jessica, Golinko Michael S, Yan Alan, Flattau Anna, Tomic-Canic Marjana, Brem Harold
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
World J Surg. 2009 Jul;33(7):1396-402. doi: 10.1007/s00268-009-0024-4.
Infection in severe pressure ulcers can lead to sepsis with a 6-month mortality as high as 68%.
Operative records of 142 consecutive operative debridements on 60 patients in a dedicated wound healing inpatient unit were reviewed, from the Wound Electronic Medical Record, for identification of key steps in debridement technique, mortality, unexpected returns, and time to discharge following debridement.
The mean age of the patients was 73.1 years, and 45% were men. Most wounds (53%) were located on the hip (ischial or trochanteric); others were on the sacrum (32%) and the heels (14%). The mean initial wound area prior to debridement was 14.0 cm(2), and 83% of debridements were performed on stage IV pressure ulcers. The postoperative hospital stay averaged 4.1 days. Key steps in the technique included (1) exposure of areas of undermining by excising overlying tissue; (2) removal of callus from wound edges; (3) removal of all grossly infected tissue; and (4) obtaining a biopsy of the deep tissue after debridement of all nonviable or infected tissue for culture and pathology to determine the presence of infection, fibrosis, and granulation tissue. There was one death 9 days post-debridement of a sacral ulcer and one unplanned return to the operating room for bleeding 8 days post-debridement.
Operative debridement of pressure ulcers is safe, despite the medical co-morbidities in patients with severe pressure ulcers. Proper debridement technique may prevent sepsis and death in patients with multiple co-morbid conditions.
严重压疮感染可导致败血症,6个月死亡率高达68%。
回顾了在一个专门的伤口愈合住院单元中,60例患者连续142次手术清创的手术记录,这些记录来自伤口电子病历,以确定清创技术的关键步骤、死亡率、意外返回情况以及清创后的出院时间。
患者的平均年龄为73.1岁,45%为男性。大多数伤口(53%)位于髋部(坐骨或转子部位);其他伤口位于骶骨(32%)和足跟(14%)。清创前的平均初始伤口面积为14.0平方厘米,83%的清创手术针对IV期压疮进行。术后平均住院时间为4.1天。该技术的关键步骤包括:(1)切除覆盖组织以暴露潜行区域;(2)清除伤口边缘的胼胝;(3)清除所有严重感染的组织;(4)在清除所有无活力或感染组织后,对深部组织进行活检,以进行培养和病理检查,确定是否存在感染、纤维化和肉芽组织。骶骨溃疡清创术后9天有1例死亡,清创术后8天有1例因出血意外返回手术室。
尽管严重压疮患者存在多种内科合并症,但手术清创治疗压疮是安全的。正确的清创技术可预防合并多种病症患者发生败血症和死亡。