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自身免疫性甲状腺功能减退症和狼疮样综合征。

Autoimmune hypothyroidism and lupus-like syndrome.

机构信息

Division of Nephrology, Department of Internal Medicine, Eskişehir Osmangazi University, Eskisehir, Turkey.

出版信息

Rheumatol Int. 2010 Feb;30(4):519-21. doi: 10.1007/s00296-009-0954-z. Epub 2009 May 15.

DOI:10.1007/s00296-009-0954-z
PMID:19444448
Abstract

The frequency of thyroid disorders, particularly Hashimoto's thyroiditis, may be increased in patients with connective tissue diseases. Both hypothyroidism and connective tissue diseases often cause muscle and joint aches, pains and stiffness. Skin, renal and cardiovascular involvement seen in the course of autoimmune hypothyroidism (AIH) may simulate connective tissue diseases such as systemic lupus erythematosus (SLE). We herein report a case of AIH who presented with massive proteinuria, haematuria, pleural fluid and arthritis simulating SLE.

摘要

甲状腺疾病的发病率,尤其是桥本甲状腺炎,可能在结缔组织疾病患者中增加。甲状腺功能减退和结缔组织疾病通常都会导致肌肉和关节疼痛、疼痛和僵硬。自身免疫性甲状腺功能减退症(AIH)过程中出现的皮肤、肾脏和心血管受累可能会模拟如系统性红斑狼疮(SLE)等结缔组织疾病。本文报告了一例 AIH 病例,其表现为大量蛋白尿、血尿、胸腔积液和关节炎,模拟 SLE。

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本文引用的文献

1
A case of autoimmune thyroiditis and membranoproliferative glomerulonephritis.一例自身免疫性甲状腺炎合并膜增生性肾小球肾炎。
Pediatr Nephrol. 2009 Jan;24(1):193-7. doi: 10.1007/s00467-007-0668-y. Epub 2007 Nov 16.
2
Frequency of rheumatic diseases in patients with autoimmune thyroid disease.自身免疫性甲状腺疾病患者中风湿性疾病的发病率。
Rheumatol Int. 2007 Apr;27(6):575-7. doi: 10.1007/s00296-006-0263-8. Epub 2006 Nov 11.
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Chronic autoimmune thyroiditis and rheumatic manifestations.慢性自身免疫性甲状腺炎与风湿性表现。
Joint Bone Spine. 2004 Jul;71(4):275-83. doi: 10.1016/j.jbspin.2003.06.005.
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[Membranoproliferative glomerulonephritis associated with autoimmune thyroiditis].[与自身免疫性甲状腺炎相关的膜增生性肾小球肾炎]
Nefrologia. 2004;24 Suppl 3:43-8.
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IgA nephropathy and autoimmune thyroiditis.IgA肾病与自身免疫性甲状腺炎。
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Membranous nephropathy associated with thyroid disorders.与甲状腺疾病相关的膜性肾病。
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Studies of immune-complex glomerulonephritis mediated by human thyroglobulin.由人甲状腺球蛋白介导的免疫复合物性肾小球肾炎的研究。
N Engl J Med. 1981 May 14;304(20):1212-5. doi: 10.1056/NEJM198105143042006.
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Mild hypothyroidism and oedema: evidence for increased capillary permeability to protein.轻度甲状腺功能减退与水肿:蛋白质毛细血管通透性增加的证据。
Clin Endocrinol (Oxf). 1983 Jun;18(6):627-35. doi: 10.1111/j.1365-2265.1983.tb00601.x.
9
Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity.培养的人甲状腺细胞表面存在器官特异性“微粒体”自身抗原:其与补体介导的细胞毒性有关。
Clin Exp Immunol. 1981 Aug;45(2):316-28.
10
Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease.自身免疫性甲状腺疾病中的终末补体复合物和C1/C1抑制剂复合物
Clin Exp Immunol. 1989 Jul;77(1):25-30.