POEMS综合征中的肾脏受累情况。
Renal involvement in POEMS syndrome.
作者信息
Mizuiri S, Mitsuo K, Sakai K, Hayashi I, Suzuki T, Nagai Y, Ohara T, Hasegawa A, Kawamura S
机构信息
Department of Nephrology, Toho University School of Medicine, Tokyo, Japan.
出版信息
Nephron. 1991;59(1):153-6. doi: 10.1159/000186536.
We describe a patient with POEMS syndrome whose renal biopsy specimen also showed nephropathy. Immunoelectron microscopy of the renal biopsy revealed the localization of immunoglobulin (IgA and lambda light chain) in the subendothelial space of the glomerular capillaries, a previously unrecognized finding. We conclude that the renal pathology in POEMS syndrome is unusual and distinct from microangiopathic glomerular involvement or idiopathic mesangiocapillary glomerulonephritis.
我们描述了一名患有POEMS综合征的患者，其肾活检标本也显示出肾病。肾活检的免疫电子显微镜检查显示免疫球蛋白（IgA和λ轻链）定位于肾小球毛细血管的内皮下间隙，这是一个以前未被认识到的发现。我们得出结论，POEMS综合征中的肾脏病理情况不寻常，有别于微血管病性肾小球受累或特发性系膜毛细血管性肾小球肾炎。
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