Ohkawa M, Motoi I, Hirano S, Okasho A, Hisazumi H
Department of Urology, School of Medicine, Kanazawa University, Japan.
Nephron. 1991;59(1):80-3. doi: 10.1159/000186523.
Biochemical analysis of renal cyst fluid was performed in 53 patients with simple renal cysts including 2 infected cases. The composition of noninfected cyst fluid tended to parallel that of serum. Additionally, the penetration of amikacin into cyst fluid was studied in 2 infected and in 11 noninfected patients following a single 200-mg intramuscular injection of amikacin. Drug levels in the fluid were below detection limit in the noninfected and approximately half or less of the serum values in the infected patients. These data may explain one of the reasons why infection of simple renal cysts is highly resistant to antimicrobial chemotherapy. The value of treatment by percutaneous aspiration and drainage of infected cysts is emphasized.
对53例单纯性肾囊肿患者（包括2例感染病例）的肾囊肿液进行了生化分析。未感染囊肿液的成分往往与血清成分相似。此外，在2例感染患者和11例未感染患者单次肌肉注射200mg阿米卡星后，研究了阿米卡星在囊肿液中的渗透情况。未感染患者囊肿液中的药物水平低于检测限，而感染患者囊肿液中的药物水平约为血清值的一半或更低。这些数据可能解释了单纯性肾囊肿感染对抗菌化疗高度耐药的原因之一。强调了经皮穿刺抽吸和引流感染性囊肿治疗的价值。
