Hawley John A
Exercise Metabolism Group, School of Medical Sciences, RMIT University, Bundoora, Australia.
Appl Physiol Nutr Metab. 2009 Jun;34(3):355-61. doi: 10.1139/H09-023.
Simultaneously training for both strength and endurance results in a compromised adaptation, compared with training for either exercise mode alone. This has been variously described as the concurrent training effect or the interference effect. It now appears that the genetic and molecular mechanisms of adaptation induced by resistance- and endurance-based training are distinct, with each mode of exercise activating and (or) repressing specific subsets of genes and cellular signalling pathways. This brief review will summarize our current understanding of the molecular responses to strength and endurance training, and will examine the molecular evidence for an interference effect when concurrent training is undertaken. A better understanding of the activation and interaction of the molecular pathways in response to these different modes of exercise will permit sport scientists to develop improved training programs capable of maximizing both strength and endurance.
与单独进行力量训练或耐力训练相比，同时进行力量和耐力训练会导致适应性受损。这被不同地描述为同时训练效应或干扰效应。现在看来，基于阻力训练和耐力训练所诱导的适应性的遗传和分子机制是不同的，每种运动模式都会激活和（或）抑制特定的基因和细胞信号通路子集。这篇简短的综述将总结我们目前对力量和耐力训练分子反应的理解，并将研究进行同时训练时干扰效应的分子证据。更好地理解这些不同运动模式下分子途径的激活和相互作用，将使体育科学家能够制定出能够同时最大化力量和耐力的改进训练计划。
