Mataradze G D, Kurabekova R M, Rozen V B
Probl Endokrinol (Mosk). 1991 May-Jun;37(3):54-6.
A study was made of the role of hypophyseal hormones in the regulation of the sex-associated level of corticosteroid-binding globulin (CBG) in the serum of female and male rats. Pituitary body removal did not change the level of CBG in males but caused its decrease in females to the level in intact males. Ectopic transplantation of the homologous pituitary body under the renal capsule increased the level of CBG in animals of both sexes. Intermittent infusion of STH did not change CBG content in hypophysectomized female rats and lowered it in intact females. A negative effect of androgens on the studied sign did not manifest itself either against a background of hypophysectomy or hypophyseal ectopy. Corticosteroids and thyroid hormones preserved their effects with regard to the level of CBG in hypophysectomized rats.
对垂体激素在调节雌性和雄性大鼠血清中与性别相关的皮质类固醇结合球蛋白（CBG）水平方面的作用进行了研究。摘除垂体并未改变雄性大鼠的CBG水平，但导致雌性大鼠的CBG水平降至完整雄性大鼠的水平。将同种垂体异位移植到肾包膜下可提高两性动物的CBG水平。间歇性注射生长激素（STH）对垂体切除的雌性大鼠的CBG含量没有影响，但可降低完整雌性大鼠的CBG含量。无论是在垂体切除还是垂体异位的背景下，雄激素对所研究指标均无负面影响。皮质类固醇和甲状腺激素对垂体切除大鼠的CBG水平仍有影响。
