Paul Yash
Maharaja Agrasen Hospital, Vidhyadhar Nagar, Jaipur 302023, India.
Vaccine. 2009 Jun 8;27(28):3700-3. doi: 10.1016/j.vaccine.2009.03.078. Epub 2009 Apr 16.
Oral polio vaccine has reduced the incidence of polio in India and many states have been polio free for a long time while occasional polio cases are occurring in some states. On the other hand more than 96% of polio cases being reported in India are occurring in Uttar Pradesh and Bihar. The current polio scenario indicates that oral polio vaccines cannot eradicate polio from Uttar Pradesh and Bihar because some children from these two states show poor response to OPV. There is an urgent need for re-appraisal of polio eradication strategy.
口服脊髓灰质炎疫苗降低了印度脊髓灰质炎的发病率，许多邦长期无脊髓灰质炎病例，而一些邦偶尔仍有病例发生。另一方面，印度报告的脊髓灰质炎病例中，超过96%发生在北方邦和比哈尔邦。目前的脊髓灰质炎情况表明，口服脊髓灰质炎疫苗无法在北方邦和比哈尔邦根除脊髓灰质炎，因为这两个邦的一些儿童对口服脊髓灰质炎疫苗反应不佳。迫切需要重新评估脊髓灰质炎根除策略。
