L'Oréal, Laboratories de Recherche, Aulnay-sous-Bois, France.
Int J Cosmet Sci. 1979 Oct;1(5):303-14. doi: 10.1111/j.1467-2494.1979.tb00224.x.
Synopsis Although aqueous dispersions of lipids in the form of particles having a lamellar structure (liposomes) are already known as excellent vehicles for pharmaceutical substances, their usefulness in cosmetic formulations has not been demonstrated. The present work shows the advantages obtained by application of such systems to the skin, and in particular the use of non-ionic lipids in aqueous dispersions. Thus, in comparison with classical formulations such as emulsions, these systems exhibit lower toxicity and permit closer control of the availability of active substances at the stratum corneum. As examples, compositions suitable for skin moisturising and for tanning products are presented.
概要 虽然具有层状结构（脂质体）的颗粒形式的脂类的水性分散体已被公认为药物物质的优良载体，但它们在化妆品配方中的用途尚未得到证实。本工作显示了将此类系统应用于皮肤所获得的优点，特别是在水性分散体中使用非离子脂质。因此，与经典制剂（如乳液）相比，这些系统的毒性更低，并且可以更紧密地控制角质层中活性物质的可用性。本文以适合皮肤保湿和晒黑产品的配方为例。
