Department of Hearing and Speech, Children's National Medical Center, Washington, DC 20010, USA.
Dysphagia. 2009 Dec;24(4):412-22. doi: 10.1007/s00455-009-9219-y. Epub 2009 May 27.
The purpose of this study was to investigate comparability of viscosity of liquids used in assessment and treatment of infants with dysphagia. Goals of this study were as follows: (1) Establish baseline viscosity values for (a) the commercial barium assessment liquids of varying thicknesses and (b) clinically typical infant formula thickened with varied thickeners. (2) Compare the baseline viscosities of the various liquids for correlation of values. We attempted to mimic real-world situations and recreate clinical assessment and treatment conditions. We also identified and made every effort to control typical clinical variables, e.g., mixer and mixing procedure, brand of product, and temperature of liquid. The method of measurement was based on rheologic principles and used a Brookfield Engineering LVDV II + Pro Cone/Plate Viscometer at spindle and speed combinations to maximize shear rates consistent with swallowing. Statistically, there was no comparability between barium and formula mixtures, regardless of thickener utilized. The implications of these findings and the need to develop a standardized means of thickening formula to a viscosity comparable to the assessment materials are discussed.
本研究旨在探讨用于评估和治疗吞咽困难婴儿的液体粘度的可比性。本研究的目的如下：（1）确定（a）商业钡评估液的不同厚度和（b）用不同增稠剂增稠的临床典型婴儿配方的基础粘度值。（2）比较各种液体的基础粘度值，以进行相关性分析。我们试图模拟真实世界的情况，并重现临床评估和治疗条件。我们还确定并尽一切努力控制典型的临床变量，例如混合器和混合程序、产品品牌和液体温度。测量方法基于流变学原理，使用 Brookfield Engineering LVDV II + Pro 锥/板粘度计在最大剪切速率与吞咽一致的情况下，在轴和速度组合下进行测量。从统计学上看，无论使用何种增稠剂，钡和配方混合物之间都没有可比性。讨论了这些发现的意义以及需要开发一种标准化的方法来将配方增稠到与评估材料可比的粘度。
