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挪威养老院中的秘密用药仍然是个问题吗?一项横断面研究。

Is covert medication in Norwegian nursing homes still a problem? A cross-sectional study.

作者信息

Kirkevold Oyvind, Engedal Knut

机构信息

Norwegian Centre for Dementia Research, Vestfold Mental Health Trust, Tønsberg, Norway.

出版信息

Drugs Aging. 2009;26(4):333-44. doi: 10.2165/00002512-200926040-00004.

Abstract

BACKGROUND AND OBJECTIVE

The practice of hiding medicines in nursing home patients' food or beverages is described in only a few scientific papers. An earlier study conducted in 1999/2000 showed that covert medication was common in Norwegian nursing homes, with 11% of patients in regular nursing home units (RUs) and 17% of those in special care units for patients with dementia (SCUs) receiving at least one covert medication during the last 7 days. However, that study included few details about the medications involved. Therefore, we designed a study to obtain more detailed information about the practice of covert medication. The objectives of the study were to describe how widespread the practice is, identify the reasons for giving the medicine in disguise, determine what kinds of medicine are given in disguise, and establish who makes the decision about covert medication.

METHODS

We collected data on 1,943 patients (623 in SCUs and 1,320 in RUs) in southeast Norway between October 2006 and February 2007. The information collected included what kind of drugs the patients received, what form the drugs were administered in and how the drugs were given. Patient characteristics such as age, sex, the patient's level of function in terms of activities of daily living (ADL), mental capacity and behavioural and psychological symptoms were also recorded. Ward characteristics such as the type of ward, the number of beds in the ward and the number of carers working on each shift were also documented. Descriptive statistics of the distribution of covert medication were obtained and the findings from SCUs and RUs were compared. The same approach was taken regarding information relating to who took the decision and how the practice was documented. A multilevel logistic regression analysis was performed to examine which patient and ward characteristics were associated with covert medication.

RESULTS

Each patient was given on average 6.5 different medications on a regular basis every day. Nearly a quarter (23.5%) of patients who received medications had drugs mixed in food or beverages. Fourteen percent of the patients in SCUs and nearly 10% of the patients in RUs received medicine blended in food or beverages without their knowledge (covert medication). Compared with patients who were treated openly, a significantly higher proportion of patients who were treated covertly received antipsychotics (20% vs 30%, respectively; p < 0.001). In most cases, the decision to administer covert medication was made by the staff together with the physician or by the physician alone (61.4% of occasions in SCUs and 52.8% in RUs). About two-thirds of cases of covert medication had been documented to some extent in the patients' records. Low mental capacity, low ADL function and the presence of agitation and learning disability were associated with covert medication. Of the ward characteristics, only staying in SCUs was associated with covert medication.

CONCLUSION

Our study presents evidence suggesting that the practice of covert medication may still be a problem in Norwegian nursing homes. The frequency of this practice has been only slightly reduced in the period 2000-7, but the practice is more frequently recorded in the patient's records and the physician is today more often involved in the decision to give medicine covertly compared with 7 years ago.

摘要

背景与目的

仅有少数科学论文描述了在疗养院患者的食物或饮料中隐藏药物的做法。1999/2000年进行的一项早期研究表明,在挪威疗养院中,秘密给药很常见,在普通疗养院病房(RU)中,11%的患者以及在痴呆症患者特殊护理病房(SCU)中,17%的患者在过去7天内至少接受过一次秘密给药。然而,该研究几乎没有涉及所涉药物的详细信息。因此,我们设计了一项研究以获取有关秘密给药做法的更详细信息。该研究的目的是描述这种做法的普遍程度,确定伪装给药的原因,确定伪装给药的药物种类,并确定谁做出秘密给药的决定。

方法

我们收集了2006年10月至2007年2月期间挪威东南部1943名患者(SCU中有623名,RU中有1320名)的数据。收集的信息包括患者接受何种药物、药物的给药形式以及给药方式。还记录了患者的特征,如年龄、性别、患者在日常生活活动(ADL)方面的功能水平、心理能力以及行为和心理症状。病房特征,如病房类型、病房床位数以及每个班次工作的护理人员数量也进行了记录。获得了秘密给药分布的描述性统计数据,并比较了SCU和RU的结果。对于谁做出决定以及如何记录这种做法的相关信息,采用了相同的方法。进行了多水平逻辑回归分析,以检查哪些患者和病房特征与秘密给药相关。

结果

每位患者每天平均常规服用6.5种不同药物。近四分之一(23.5%)接受药物治疗的患者的药物被混入食物或饮料中。SCU中14%的患者以及RU中近10%的患者在不知情的情况下接受了混入食物或饮料中的药物(秘密给药)。与公开治疗的患者相比,接受秘密治疗的患者中接受抗精神病药物治疗的比例显著更高(分别为20%和30%;p<0.001)。在大多数情况下,秘密给药的决定由工作人员与医生共同做出或由医生单独做出(SCU中61.4%的情况,RU中52.8%的情况)。约三分之二的秘密给药病例在患者记录中得到了一定程度的记录。心理能力低、ADL功能低以及存在躁动和学习障碍与秘密给药相关。在病房特征方面,只有住在SCU与秘密给药相关。

结论

我们的研究提供的证据表明,在挪威疗养院中,秘密给药做法可能仍然是一个问题。在2000 - 2007年期间,这种做法的频率仅略有降低,但现在这种做法在患者记录中记录得更频繁,与7年前相比,如今医生更常参与做出秘密给药的决定。

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