Pomerri F, Dodi G, Nardin M, Muzzio P C
Department of Medical Diagnostic Sciences and Special Therapies, University of Padua, Via Giustiniani 2, Padua, Italy.
Radiol Med. 2009 Sep;114(6):925-34. doi: 10.1007/s11547-009-0409-3. Epub 2009 May 30.
This study was done to determine colonic transit times in healthy Italian adults.
Institutional review board approval and informed patient consent were obtained. Colonic segmental radiopaque markers were counted and transit times calculated in 36 healthy subjects studied using a technique involving daily radiopaque marker ingestion and single radiological visit, with oral administration of 8-10 ml of a thick barium paste as a colonic trace for the marker count. Two independent radiologists counted the marker twice. Observer agreement was assessed using comparison analysis.
There was very good observer agreement for the segmental marker counts. The upper limit for colonic transit times was: 45.6 h in the colon as a whole, 31.2 h in the right colon, 19.2 h in the left colon and 16.8 h in the rectosigmoid. Colonic transit times were not gender-related.
In healthy subjects, a barium trace affords optimal visibility of the different colonic segments, enabling accurate location of all markers and thus providing an anatomy-related, repeatable and reproducible fluoroscopic segmental marker count. We suggest that the reference values for normal colonic transit times could be adopted for Italian people irrespective of gender.
本研究旨在确定健康意大利成年人的结肠转运时间。
获得机构审查委员会批准并取得患者知情同意。对36名健康受试者进行结肠节段性不透射线标志物计数并计算转运时间，采用的技术包括每日摄入不透射线标志物和单次放射学检查，口服8 - 10毫升浓稠钡糊作为结肠标志物计数的示踪剂。两名独立的放射科医生对标志物进行两次计数。使用比较分析评估观察者间的一致性。
节段性标志物计数的观察者间一致性非常好。结肠转运时间的上限为：整个结肠45.6小时，右结肠31.2小时，左结肠19.2小时，直肠乙状结肠16.8小时。结肠转运时间与性别无关。
在健康受试者中，钡剂示踪能使不同结肠节段具有最佳可视性，可准确确定所有标志物的位置，从而提供与解剖结构相关、可重复且能再现的荧光透视节段性标志物计数。我们建议，无论性别，意大利人可采用正常结肠转运时间的参考值。
