Singh A B, Yadav D K, Maurya R, Srivastava A K
Division of Biochemistry, Central Drug Research Institute, Lucknow, India.
Nat Prod Res. 2009;23(9):876-82. doi: 10.1080/14786410802420416.
The article reveals the antihyperglycaemic activity of the alpha-amyrin acetate (alpha-AA) isolated from the aerial roots of the Ficus bengalensis in normal and diabetic rats and model of type-2 diabetes, i.e. db/db mice. The oral administration of alpha-AA significantly improved the diabetic condition in streptozotocin-induced diabetic rats and in diabetic db/db mice at 50 mg kg(-1) dose level.
该文章揭示了从孟加拉榕气生根中分离得到的醋酸α-香树脂醇（α-AA）在正常大鼠和糖尿病大鼠以及2型糖尿病模型即db/db小鼠中的降血糖活性。口服α-AA在50 mg kg(-1)剂量水平时，能显著改善链脲佐菌素诱导的糖尿病大鼠和糖尿病db/db小鼠的糖尿病状况。
