Jahan Rownak, Al-Nahain Abdullah, Majumder Snehali, Rahmatullah Mohammed
Department of Biotechnology & Genetic Engineering, University of Development Alternative, Dhanmondi, Dhaka 1209, Bangladesh.
Department of Pharmacy, University of Development Alternative, Dhanmondi, Dhaka 1209, Bangladesh.
Int Sch Res Notices. 2014 Oct 29;2014:385969. doi: 10.1155/2014/385969. eCollection 2014.
Eclipta alba can be found growing wild in fallow lands of Bangladesh where it is considered as a weed by farmers. Traditional medicinal systems of the Indian subcontinent countries as well as tribal practitioners consider the plant to have diverse medicinal values and use it commonly for treatment of gastrointestinal disorders, respiratory tract disorders (including asthma), fever, hair loss and graying of hair, liver disorders (including jaundice), skin disorders, spleen enlargement, and cuts and wounds. The plant has several phytoconstituents like wedelolactone, eclalbasaponins, ursolic acid, oleanolic acid, luteolin, and apigenin. Pharmacological activities of plant extracts and individual phytoconstituents have revealed anticancer, hepatoprotective, snake venom neutralizing, anti-inflammatory, and antimicrobial properties. Phytoconstituents like wedelolactone and ursolic and oleanolic acids as well as luteolin and apigenin can form the basis of new drugs against cancer, arthritis, gastrointestinal disorders, skin diseases, and liver disorders.
白花蟛蜞菊在孟加拉国的休耕地上野生生长,在那里它被农民视为杂草。印度次大陆国家的传统医学体系以及部落行医者都认为这种植物具有多种药用价值,并常用于治疗胃肠道疾病、呼吸道疾病(包括哮喘)、发烧、脱发和白发、肝脏疾病(包括黄疸)、皮肤疾病、脾脏肿大以及伤口。该植物含有多种植物成分,如蟛蜞菊内酯、蟛蜞菊皂苷、熊果酸、齐墩果酸、木犀草素和芹菜素。植物提取物和单个植物成分的药理活性已显示出抗癌、保肝、中和蛇毒、抗炎和抗菌特性。像蟛蜞菊内酯、熊果酸和齐墩果酸以及木犀草素和芹菜素这样的植物成分可以成为开发抗癌、关节炎、胃肠道疾病、皮肤病和肝脏疾病新药的基础。