D'Amato G, De Palma R, Verga A, Martucci P, Liccardi G, Lobefalo G
Department of Pulmonary Diseases, Hospital A. Cardarelli Naples, Italy.
Ann Allergy. 1991 Oct;67(4):421-4.
In patients with respiratory allergy to pollen it is common to correlate the onset, duration and intensity of clinical symptoms with the count of atmospheric allergenic pollen grains. Pollen counts, however, may not reflect the total airborne allergen exposure since previous data suggest that pollen allergens may also be carried in microaerosol suspensions. These microdroplets may penetrate deeply into the airways, where pollen grains are too large to penetrate, eventually inducing asthma. The origin of these allergenic aerosols is still uncertain. We investigated whether antigenic activity is present in vegetative parts of allergenic plants. We have used extracts from leaves and stems of Parietaria judaica and Dactylis glomerata to evaluate patients with allergic sensitization to pollen allergens of these plants (19 grass-sensitive patients and 23 Parietaria sensitive). By using skin prick testing and RAST to stem and leaf extracts other than pollen extracts we observed that most patients sensitive to grass or Parietaria pollen had small responses to extracts of stem or leaf. We conclude that allergenic components are present throughout most of Parietaria judaica and Dactylis glomerata plants, most highly concentrated in the pollen but present in the leaves with a trace in the stems.
在对花粉有呼吸道过敏的患者中，通常会将临床症状的发作、持续时间和强度与大气中致敏花粉颗粒的计数相关联。然而，花粉计数可能无法反映空气中过敏原的总暴露量，因为先前的数据表明花粉过敏原也可能存在于微气溶胶悬浮液中。这些微滴可能会深入气道，而花粉颗粒太大无法穿透，最终引发哮喘。这些致敏气溶胶的来源仍不确定。我们研究了致敏植物的营养部分是否存在抗原活性。我们使用了犹太墙草和鸭茅的叶和茎提取物，来评估对这些植物的花粉过敏原过敏致敏的患者（19名对草敏感的患者和23名对犹太墙草敏感的患者）。通过对茎和叶提取物而非花粉提取物进行皮肤点刺试验和放射变应原吸附试验，我们观察到，大多数对草或犹太墙草花粉敏感的患者对茎或叶提取物的反应较小。我们得出结论，犹太墙草和鸭茅的大部分植物中都存在致敏成分，其中花粉中含量最高，叶子中也有，茎中含量微量。
