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巴祖卡单光子发射计算机断层扫描(BazookaSPECT)的最新进展:实时数据处理与伽马射线显微镜的研发

Recent advances in BazookaSPECT: Real-time data processing and the development of a gamma-ray microscope.

作者信息

Miller Brian W, Barrett Harrison H, Furenlid Lars R, Barber H Bradford, Hunter Robert J

机构信息

Department of Radiology, University of Arizona, Tucson, AZ 85724, USA.

出版信息

Nucl Instrum Methods Phys Res A. 2008 Jun 11;591(1):272-275. doi: 10.1016/j.nima.2008.03.072.

DOI:10.1016/j.nima.2008.03.072
PMID:19526045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2597870/
Abstract

Recent advances have been made with the BazookaSPECT detector, a high-resolution CCD-based gamma camera which utilizes an MCP-based image intensifier for upfront optical gain. Operating the gamma camera at high frame rates leads to a massive amount of data throughput, thereby inducing the need for real-time processing. We have developed and implemented a list-mode algorithm which allows for real-time data acquisition and processing at high frame rates. This is accomplished with a graphics processing unit (GPU), which provides processing capabilities in addition to the CPU. We have also developed a gamma-ray microscope based on the BazookaSPECT detector and micro-coded apertures. Experimental phantom images show the gamma-ray microscope having an estimated reconstruction resolution of ~30 μm, an unprecedented resolution in gamma-ray imaging.

摘要

巴祖卡单光子发射计算机断层扫描(SPECT)探测器取得了最新进展,这是一种基于电荷耦合器件(CCD)的高分辨率伽马相机,它利用基于微通道板(MCP)的图像增强器实现前期光学增益。以高帧率操作伽马相机导致大量的数据吞吐量,从而引发了对实时处理的需求。我们开发并实施了一种列表模式算法,该算法允许以高帧率进行实时数据采集和处理。这是通过图形处理单元(GPU)实现的,它除了提供中央处理器(CPU)的处理能力外,还具备额外的处理能力。我们还基于巴祖卡SPECT探测器和微编码孔径开发了一种伽马射线显微镜。实验体模图像显示,该伽马射线显微镜的估计重建分辨率约为30微米,这在伽马射线成像中是前所未有的分辨率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/11c6d46f45cc/nihms56360f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/6c202da490b1/nihms56360f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/178afbb56844/nihms56360f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/12cef70d7bab/nihms56360f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/b76eca5cb69b/nihms56360f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/11c6d46f45cc/nihms56360f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/6c202da490b1/nihms56360f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/178afbb56844/nihms56360f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/12cef70d7bab/nihms56360f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/b76eca5cb69b/nihms56360f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd84/2597870/11c6d46f45cc/nihms56360f5.jpg

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