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利用病假记录预测在职人群未来的抑郁症:GAZEL队列研究的前瞻性结果。

Using sickness absence records to predict future depression in a working population: prospective findings from the GAZEL cohort.

作者信息

Melchior Maria, Ferrie Jane E, Alexanderson Kristina, Goldberg Marcel, Kivimaki Mika, Singh-Manoux Archana, Vahtera Jussi, Westerlund Hugo, Zins Marie, Head Jenny

机构信息

National Institutes of Health and Medical Research (INSERM U687), 94807 Villejuif Cédex, France.

出版信息

Am J Public Health. 2009 Aug;99(8):1417-22. doi: 10.2105/AJPH.2008.142273. Epub 2009 Jun 18.

Abstract

OBJECTIVES

We tested the hypothesis that sickness absence from work predicts workers' risk of later depression.

METHODS

Study participants (n = 7391) belonged to the French GAZEL cohort of employees of the national gas and electricity company. Sickness absence data (1996-1999) were obtained from company records. Participants' depression in 1996 and 1999 was assessed with the Center for Epidemiologic Studies-Depression (CES-D) scale. The analyses were controlled for baseline age, gender, marital status, occupational grade, tobacco smoking status, alcohol consumption, subthreshold depressive symptoms, and work stress.

RESULTS

Among workers who were free of depression in 1996, 13% had depression in 1999. Compared with workers with no sickness absence during the study period, those with sickness absence were more likely to be depressed at follow-up (for 1 period of sickness absence, fully adjusted odds ratio [OR] = 1.53, 95% confidence interval [CI] = 1.28, 1.82; for 2 or more periods, fully adjusted OR = 1.95, 95% CI = 1.61, 2.36). Future depression was predicted both by psychiatric and nonpsychiatric sickness absence (fully adjusted OR = 3.79 [95% CI = 2.81, 5.10] and 1.41 [95% CI = 1.21, 1.65], respectively).

CONCLUSIONS

Sickness absence records may help identify workers vulnerable to future depression.

摘要

目的

我们检验了因病缺勤可预测员工日后患抑郁症风险这一假设。

方法

研究参与者(n = 7391)来自法国国家天然气和电力公司员工的GAZEL队列。因病缺勤数据(1996 - 1999年)取自公司记录。使用流行病学研究中心抑郁量表(CES - D)评估参与者在1996年和1999年的抑郁情况。分析时对基线年龄、性别、婚姻状况、职业等级、吸烟状况、饮酒量、亚阈值抑郁症状和工作压力进行了控制。

结果

在1996年无抑郁症的员工中,13%在1999年患抑郁症。与研究期间无因病缺勤的员工相比,有因病缺勤的员工在随访时更易患抑郁症(因病缺勤1次,完全调整后的比值比[OR] = 1.53,95%置信区间[CI] = 1.28, 1.82;因病缺勤2次或更多次,完全调整后的OR = 1.95,95% CI = 1.61, 2.36)。精神疾病和非精神疾病导致的因病缺勤均可预测未来患抑郁症的风险(完全调整后的OR分别为3.79 [95% CI = 2.81, 5.10]和1.41 [95% CI = 1.21, 1.65])。

结论

因病缺勤记录可能有助于识别易患未来抑郁症的员工。

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