Thiry M, Lecoq-Xhonneux F, Dheur I, Renard A, De Kinkelin P
Eurogentec SA, Liège Belgium.
Biochim Biophys Acta. 1991 Nov 11;1090(3):345-7. doi: 10.1016/0167-4781(91)90200-6.
A cDNA clone encoding for the glycoprotein of the viral haemorrhagic scepticaemia virus, a fish rhabdovirus, has been sequenced. The cDNA was 2035 bp long and contained two open reading frames (ORF). A 1523 bp ORF corresponded to the glycoprotein and was adjacent, on its 5' side, to an incomplete 372 bp ORF. Although the protein encoded by this ORF displayed no similarity with other rhabdovirus proteins, it was supposed that the cDNA had been reverse-transcribed from a readthrough mRNA encoding successively for the M2 and the G proteins.
已对编码病毒性出血性败血症病毒(一种鱼类弹状病毒)糖蛋白的cDNA克隆进行了测序。该cDNA长2035 bp,包含两个开放阅读框(ORF)。一个1523 bp的ORF对应于糖蛋白,并且在其5'侧与一个不完整的372 bp ORF相邻。尽管该ORF编码的蛋白质与其他弹状病毒蛋白没有相似性,但推测该cDNA是从依次编码M2和G蛋白的通读mRNA逆转录而来的。