Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Cambridge, MA 02138, USA.
Eur Child Adolesc Psychiatry. 2010 Feb;19(2):107-12. doi: 10.1007/s00787-009-0041-8. Epub 2009 Jun 19.
The main aim of this study was to examine the moderating effects of attention deficit hyperactivity disorder (ADHD) on anxiety disorders in children. Data were analyzed from a large referred sample of children with anxiety disorder without comorbid ADHD (anxiety disorder, N = 253), anxiety disorder plus comorbid ADHD (anxiety disorder + ADHD, N = 704), and ADHD without comorbid anxiety disorder (ADHD, N = 511). Children were comprehensively assessed, including by structured diagnostic interview (K-SADS-E). Overall rates of individual anxiety disorders, as well as age of onset and severity of illness were not significantly different in the presence of comorbid ADHD. School functioning in children with anxiety disorders was negatively impacted by the presence of comorbid ADHD. Frequency of mental health treatment in children with anxiety disorders was significantly increased in the presence of comorbid ADHD. ADHD had a limited impact on the manifestation of anxiety disorder in children suggesting that ADHD and anxiety disorders are independently expressed.
本研究的主要目的是检验注意缺陷多动障碍（ADHD）对儿童焦虑障碍的调节作用。数据分析来自一个大型的、有针对性的儿童焦虑障碍样本，包括无共患 ADHD 的焦虑障碍儿童（焦虑障碍，N=253）、伴共患 ADHD 的焦虑障碍儿童（焦虑障碍+ADHD，N=704）和无共患焦虑障碍的 ADHD 儿童（ADHD，N=511）。通过使用结构化诊断访谈（K-SADS-E）对儿童进行全面评估。在共患 ADHD 的情况下，个体焦虑障碍的总体发生率、发病年龄和疾病严重程度没有显著差异。伴共患 ADHD 的焦虑障碍儿童的学校功能受到负面影响。伴共患 ADHD 的焦虑障碍儿童的心理健康治疗频率显著增加。ADHD 对儿童焦虑障碍的表现影响有限，这表明 ADHD 和焦虑障碍是独立表现的。
