Sellappa Sudha, Balakrishnan Mythili, Raman Sangeetha, Palanisamy Subashini
Department of Biotechnology, School of Life Sciences, Karpagam University, Tamil Nadu, India.
J Oral Sci. 2009 Jun;51(2):289-92. doi: 10.2334/josnusd.51.289.
Betel quid containing areca nut and chewing tobacco is used in many parts of India. In this study we evaluated the micronuclei (MN) in buccal mucosa of healthy individuals from southern India, who were regularly chewing a mixture of betel leaf, areca nut and tobacco. A total of 44 subjects were examined. The study population included 15 chewers, 14 chewers with smoking habit and 15 controls with the mean age of 38.57 +/- 0.54, 34.50 +/- 0.95, and 33.28 +/- 0.89 years, respectively. The mean percentage of MN was 1.90 +/- 1.03 in chewers, 2.00 +/-1.12 in chewers with smoking habits and 0.81 +/- 0.66 in controls. There was no significant difference between the mean percentages of the two experimental groups. It can be concluded that a mixture of betel leaf, areca nut, and tobacco is unsafe for oral health.
含有槟榔果和嚼烟的槟榔在印度许多地区都有食用。在本研究中，我们评估了来自印度南部的健康个体颊黏膜中的微核（MN）情况，这些个体经常咀嚼槟榔叶、槟榔果和烟草的混合物。总共检查了44名受试者。研究人群包括15名咀嚼者、14名有吸烟习惯的咀嚼者和15名对照组，平均年龄分别为38.57±0.54岁、34.50±0.95岁和33.28±0.89岁。咀嚼者的微核平均百分比为1.90±1.03，有吸烟习惯的咀嚼者为2.00±1.12，对照组为0.81±0.66。两个实验组的平均百分比之间没有显著差异。可以得出结论，槟榔叶、槟榔果和烟草的混合物对口腔健康不安全。
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