Landry Marie L, Lebeck Mark G, Capuano Ana W, McCarthy Troy, Gray Gregory C
Department of Laboratory Medicine, Yale New Haven Hospital, Yale University School of Medicine, Connecticut 06520-8035, USA.
J Med Virol. 2009 Aug;81(8):1380-4. doi: 10.1002/jmv.21539.
An adenovirus outbreak occurred in New Haven, Connecticut in 2006-2007. Molecular typing revealed a twofold increase in adenovirus type 3 infections. Restriction enzyme analysis (REA) indicated that the CT outbreak was largely due to a marked increase in the novel Ad3a51 strain. This outbreak represents the first detection of Ad3a51 in the United States. While most infections were mild, children under 3 were at increased risk for severe disease and one patient with underlying disease died.
2006 - 2007年,康涅狄格州纽黑文市发生了腺病毒疫情。分子分型显示,3型腺病毒感染增加了两倍。限制性内切酶分析(REA)表明,康涅狄格州的疫情主要是由于新型Ad3a51毒株显著增加所致。此次疫情是美国首次检测到Ad3a51。虽然大多数感染症状较轻,但3岁以下儿童患重病的风险增加,一名患有基础疾病的患者死亡。