通过在磷酸钠肠道准备中添加西甲硅油来提高结肠镜检查质量。
Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation.
作者信息
Tongprasert Sasinee, Sobhonslidsuk Abhasnee, Rattanasiri Sasivimol
机构信息
Department of Medicine, Division of Gastroenterology, Faculty of Medicine Ramathibodi Hospital, Rajathevee, Bangkok, Thailand.
出版信息
World J Gastroenterol. 2009 Jun 28;15(24):3032-7. doi: 10.3748/wjg.15.3032.
Abstract
AIM
To evaluate the effectiveness of simethicone in enhancing visibility and efficacy during colonoscopy.
METHODS
A prospective, double-blind, randomized, placebo-controlled study was conducted. One hundred and twenty-four patients were allocated to receive 2 doses of sodium phosphate plus 240 mg of tablet simethicone or placebo as bowel preparation. Visibility was blindly assessed for the amount of air bubbles and adequacy of colon preparation. Total colonoscopic time, side effects of the medication, endoscopist and patient satisfaction were also compared.
RESULTS
Sodium phosphate plus simethicone, compared to sodium phosphate plus placebo, improved visibility by diminishing air bubbles (100.00% vs 42.37%, P < 0.0001) but simethicone failed to demonstrate improvement in adequacy of colon preparation (90.16% vs 81.36%, P = 0.17). Endoscopist and patient satisfaction were increased significantly in the simethicone group. However, there was no difference in the total duration of colonoscopy and side effects of the medication.
CONCLUSION
The addition of simethicone is of benefit for colonoscopic bowel preparation by diminishing air bubbles, which results in enhanced visibility. Endoscopist and patient satisfaction is also increased.
摘要
目的
评估西甲硅油在提高结肠镜检查时的视野清晰度及效果方面的有效性。
方法
开展了一项前瞻性、双盲、随机、安慰剂对照研究。124例患者被分配接受2剂磷酸钠加240毫克西甲硅油片剂或安慰剂作为肠道准备。对气泡量和结肠准备的充分程度进行了盲法评估。还比较了总结肠镜检查时间、药物副作用、内镜医师和患者的满意度。
结果
与磷酸钠加安慰剂相比，磷酸钠加西甲硅油通过减少气泡提高了视野清晰度（100.00%对42.37%，P<0.0001），但西甲硅油未能显示出结肠准备充分程度的改善（90.16%对81.36%，P=0.17）。西甲硅油组内镜医师和患者的满意度显著提高。然而，结肠镜检查的总时长和药物副作用并无差异。
结论
添加西甲硅油有助于结肠镜检查的肠道准备，可减少气泡，从而提高视野清晰度。内镜医师和患者的满意度也会提高。
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