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超越行为:威廉姆斯综合征患者的社交焦虑程度低吗?

Beyond behaviour: is social anxiety low in Williams syndrome?

机构信息

Macquarie Centre for Cognitive Science, Macquarie University, Marsfield, Sydney, NSW, 2109, Australia.

出版信息

J Autism Dev Disord. 2009 Dec;39(12):1673-81. doi: 10.1007/s10803-009-0806-4. Epub 2009 Jul 10.

DOI:10.1007/s10803-009-0806-4
PMID:19590942
Abstract

Individuals with Williams syndrome (WS) exhibit striking social behaviour that may be indicative of abnormally low social anxiety. The present research aimed to determine whether social anxiety is unusually low in WS and to replicate previous findings of increased generalised anxiety in WS using both parent and self report. Fifteen individuals with WS aged 12-28 years completed the Spence Children's Anxiety Scale (SCAS) and the Children's Automatic Thoughts Scale (CATS). Their responses were compared to clinically anxious and community comparison groups matched on mental age. The findings suggest that WS is not associated with unusually low social anxiety but that generalised anxiety symptoms and physical threat thoughts are increased in WS, relative to typically developing children.

摘要

患有威廉姆斯综合征(WS)的个体表现出显著的社交行为,这可能表明他们的社交焦虑程度异常低。本研究旨在确定 WS 患者的社交焦虑是否异常低,并使用父母和自我报告来复制 WS 患者普遍存在的广泛性焦虑增加的先前发现。15 名 12-28 岁的 WS 患者完成了斯宾塞儿童焦虑量表(SCAS)和儿童自动思维量表(CATS)。他们的反应与在心理年龄上相匹配的临床焦虑和社区对照组进行了比较。研究结果表明,WS 与异常低的社交焦虑无关,但与典型发育儿童相比,WS 患者的广泛性焦虑症状和身体威胁思维增加。

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本文引用的文献

1
The neuropsychological basis of hypersociability in Williams and Down syndrome.威廉姆斯综合征和唐氏综合征中过度社交性的神经心理学基础。
Neuropsychologia. 2007 Sep 20;45(12):2839-49. doi: 10.1016/j.neuropsychologia.2007.05.006. Epub 2007 May 21.
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The Children's Automatic Thoughts Scale in a clinical sample: psychometric properties and clinical utility.临床样本中的儿童自动思维量表:心理测量特性与临床效用
Behav Res Ther. 2007 Aug;45(8):1931-40. doi: 10.1016/j.brat.2006.09.009. Epub 2006 Oct 31.
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Frontostriatal dysfunction during response inhibition in Williams syndrome.
威廉斯综合征中的焦虑:社会行为、执行功能的作用及随时间的变化。
J Autism Dev Disord. 2018 Mar;48(3):796-808. doi: 10.1007/s10803-017-3357-0.
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Anxiety Disorders in Williams Syndrome Contrasted with Intellectual Disability and the General Population: A Systematic Review and Meta-Analysis.《威廉姆斯综合征与智力障碍和普通人群焦虑障碍的对比:系统评价和荟萃分析》
J Autism Dev Disord. 2017 Dec;47(12):3765-3777. doi: 10.1007/s10803-016-2909-z.
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Attention Bias to Emotional Faces Varies by IQ and Anxiety in Williams Syndrome.威廉姆斯综合征中,对情绪面孔的注意偏向因智商和焦虑程度而异。
J Autism Dev Disord. 2016 Jun;46(6):2174-2185. doi: 10.1007/s10803-016-2748-y.
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Variation in the Williams syndrome GTF2I gene and anxiety proneness interactively affect prefrontal cortical response to aversive stimuli.威廉姆斯综合征GTF2I基因的变异与焦虑倾向相互作用,影响前额叶皮质对厌恶刺激的反应。
Transl Psychiatry. 2015 Aug 18;5(8):e622. doi: 10.1038/tp.2015.98.
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Cortisol reactivity and performance abilities in social situations in adults with Williams syndrome.威廉姆斯综合征成人在社交情境中的皮质醇反应性与表现能力。
Am J Intellect Dev Disabil. 2013 Sep;118(5):381-93. doi: 10.1352/1944-7558-118.5.381.
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The interplay between anxiety and social functioning in Williams syndrome.威廉姆斯综合征中焦虑与社会功能之间的相互作用。
J Autism Dev Disord. 2014 May;44(5):1220-9. doi: 10.1007/s10803-013-1984-7.
9
Viewing social scenes: a visual scan-path study comparing fragile X syndrome and Williams syndrome.观看社会场景:比较脆性 X 综合征和威廉姆斯综合征的视觉扫描路径研究。
J Autism Dev Disord. 2013 Aug;43(8):1880-94. doi: 10.1007/s10803-012-1737-z.
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Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome.通过对脆性 X 综合征和威廉姆斯综合征的机制理解来概念化神经发育障碍。
Curr Opin Neurol. 2012 Apr;25(2):112-24. doi: 10.1097/WCO.0b013e328351823c.
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Biol Psychiatry. 2007 Aug 1;62(3):256-61. doi: 10.1016/j.biopsych.2006.05.041. Epub 2006 Sep 25.
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Prevalence of psychiatric disorders in 4 to 16-year-olds with Williams syndrome.患有威廉姆斯综合征的4至16岁儿童精神疾病的患病率。
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The structure of negative self-statements in children and adolescents: a confirmatory factor-analytic approach.
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"Everybody in the world is my friend" hypersociability in young children with Williams syndrome.患有威廉姆斯综合征的幼儿的“世界上每个人都是我的朋友”式高度社交性。
Am J Med Genet A. 2004 Jan 30;124A(3):263-73. doi: 10.1002/ajmg.a.20416.