Norovirus seasonality and the potential impact of climate change.

Seasonal variation in norovirus infection is a recognized but poorly understood phenomenon. It is likely to be based on biological, environmental and behavioural factors that regulate transmission, virulence and persistence of the virions in host populations. Understanding the seasonal dependency of norovirus infection is an important step towards understanding its epidemiology, with subsequent implementation of efficient measures of surveillance and control. Whether or not climate change could influence the seasonal patterns of norovirus infection, by impacting on its transmission, geographic distribution and prevalence, has not yet been considered. This review addresses the question.